ID R7UW98_CAPTE Unreviewed; 839 AA.
AC R7UW98;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 08-NOV-2023, entry version 42.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_197529 {ECO:0000313|EMBL:ELU08212.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU08212.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU08212.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU08212.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP197529}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AMQN01006822; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB299236; ELU08212.1; -; Genomic_DNA.
DR AlphaFoldDB; R7UW98; -.
DR EnsemblMetazoa; CapteT197529; CapteP197529; CapteG197529.
DR HOGENOM; CLU_007551_1_0_1; -.
DR OMA; HIRISDE; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15039; 7tmB3_Methuselah-like; 1.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR45902; LATROPHILIN RECEPTOR-LIKE PROTEIN A; 1.
DR PANTHER; PTHR45902:SF1; LATROPHILIN RECEPTOR-LIKE PROTEIN A; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR Pfam; PF01033; Somatomedin_B; 1.
DR SMART; SM00201; SO; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 559..581
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 628..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 708..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 786..805
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..79
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 557..807
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 839 AA; 94397 MW; 64F6E466216F702B CRC64;
MYTYTESPWQ HHQKLKRSDT ILCEQWNISG HSFLVSPDQT CQGSCSLSAL NDQLCFCDDL
CLIYGDCCLD YEASCLQVQK KTIEVNFTSR FQAQKLASMK CIETGFLSVL ALGRCASADD
VEAKELCEGD VDGHDARTKL ILSIPFVRND LFYANIYCAI CSGVAEWGEV DSLGEVTDVK
CDKDLGSDME NVQENTEEYF TRVKTQCKFT PKSMPLMPRD CDFFPRLDSQ SISSDENAIL
CQTYSARLHD DQQGYRNLHC ALSQGQNYSE KFDCRMSFGK APGMGGNIMP SFAMLLDLRK
FSPSTVQSNQ TCSRNFTWSE VAQGCVSPQM CKGTEQENDC MFPSEFAQYL QEEIDKNNKY
DFLFVFEETT FPDVRTAFRE FDRLYEYNSY STRLDACRSD ERELSRTDKT QMCIPKSVTT
TGLLHETLER IEDVFLEKIP NTRWMLIGNE DVFELSENGR VHIETVSRNC SLHSTVDLVE
DGVVIRVPLL LEGTNVTSCS VHEETVSLSC SDVRVVISQN LTDGVLLDIP HYVINETSAF
VCMDFMLKSE TTSAKIERLL TLVCQMLSIV SLVVTLTVYS LIPSLRTVPG RCVMCLCCAL
LLAQILLQFG SFAHNVRSLC IALAALDHWA WLASFCWMVA LAYDISSVMS KETLTDGQLH
ARQFRCYLVL GWGCPTLIVG SCLAVSIVKP QLMAYTDGSV CWISSGMTSL LFTFALPLSI
TLVFNAAFFL RTVLAIRRAM EITEHVKNAS QTQSQLVLYV RLASLMGFTW LLGLLQNALP
YAGMRYAFIV CNALQGVGIM ACFVCKRRVL RMIRSRIWKR KATDLNSSTK SRTTTVTSM
//
