ID R7UWM7_CAPTE Unreviewed; 356 AA.
AC R7UWM7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=NF-kappa-B inhibitor-like protein 1 {ECO:0000256|ARBA:ARBA00014259};
DE AltName: Full=Inhibitor of kappa B-like protein {ECO:0000256|ARBA:ARBA00030621};
DE AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 {ECO:0000256|ARBA:ARBA00030802};
GN ORFNames=CAPTEDRAFT_220681 {ECO:0000313|EMBL:ELU10704.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU10704.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU10704.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU10704.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP220681}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AMQN01005985; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQN01005986; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB297286; ELU10704.1; -; Genomic_DNA.
DR AlphaFoldDB; R7UWM7; -.
DR EnsemblMetazoa; CapteT220681; CapteP220681; CapteG220681.
DR HOGENOM; CLU_054217_0_0_1; -.
DR OMA; YVTKQHA; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007249; P:canonical NF-kappaB signal transduction; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR038753; NFKBIL1.
DR PANTHER; PTHR15263; I-KAPPA-B-LIKE PROTEIN IKBL; 1.
DR PANTHER; PTHR15263:SF1; NF-KAPPA-B INHIBITOR-LIKE PROTEIN 1; 1.
DR Pfam; PF13857; Ank_5; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 39..71
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 191..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 41801 MW; ABFDB78945FB4DF6 CRC64;
MREKYLKKLR KLLKQDKFSK LKSFFKKYDV NVNEILDEKQ NTALHIACKY GHDAIALLLI
KRGAGCLASN ADGNLPLHLA CKFALRNRHA YTDLVLPLMK NCRRSLDVRN SQGVTPRELL
SEIKDQLQGQ FHEDDSTSCE SEIEEEDWRE KLAHEVQGED MFAAYENDYQ YEGRVPNTYD
NWADSMNKQY HRKHNQPHFA STRKRSRFSG EDKNDKKPKI SDEKKEEFAK KLQEEYKKKK
EKEKNEQSKE ARKIYDLKCK AMFGPLRHKD HLHYKDIPWP FATKNCSAES VTSFLFADLA
PASSGYKDYL RQQQIRWHPD RFMQKCRERL VEADLEKIVS TVKDVSQILN ALSDKS
//
