ID R7UY63_CAPTE Unreviewed; 903 AA.
AC R7UY63;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=FCH and double SH3 domains protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_225696 {ECO:0000313|EMBL:ELU08892.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU08892.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU08892.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU08892.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP225696}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; AMQN01001029; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB298688; ELU08892.1; -; Genomic_DNA.
DR AlphaFoldDB; R7UY63; -.
DR STRING; 283909.R7UY63; -.
DR EnsemblMetazoa; CapteT225696; CapteP225696; CapteG225696.
DR HOGENOM; CLU_013546_0_0_1; -.
DR OMA; TPMMEEP; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF20; PROTEIN NERVOUS WRECK; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 8..316
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 551..612
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 666..727
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 388..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..762
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 903 AA; 100699 MW; FED8653F059341D5 CRC64;
MSPPPAKVKH GVLLKTVHAE QLSKLQLKHQ QESELLEDIR NFAKQRSTIE REYSLRERWM
AHASLLKSLI NVPAAKSDRC FWALSKLAQQ YLKRPQPPLT ELPNEDGKDF RTIHSVWRTV
LDETDRVAKI RLQASDTYLQ QIFESCKPLK SSRISVAKKE FDHLKTLQTE LSQSVSDMLK
GHKVYSEDEH LSHDARNKAA DADSKVRNKS TGIFTSLAKL QQQSAKLNNR KDTCEIKSTF
SRNEYLLALG AANAHSSRYY TSDLPELMKT LDGDLYDSIR DFFTILSTTE LECCGVTQEC
FTHILTDSTK ISRHYNNLCF LHDNLVLTDL VQYQFEPQDN DPVSKVNKDH NADVTLDQEA
KKWSMCVAKE EGKIRQHTRK MQQLIDRTAS NGKLSKGSDD SVEADHGPSS PVDVDVKLDI
FREQIRKAEL GKLKGQARLD VLRAGGVAVD GYLDEANAQM EKKDEEDSMK QTTSSVRSES
NGCSESRSIS VADPDHDSAF VCDTSSVTSQ PTAPSDSTYV NYQEEDDFVD DTFTEANSTR
SLSAGYSSGR VYPIKCFALY DFEASNGDEL SIKENEALDL IGDGDGDGWL RARNIEGQLG
FIPENYVRMA DENSDPVDPN EMSVDADPME EVTTPEASAE RISGYSSTDY EVQAASERSI
DQVVPSDGLW ARALYDYSAT CDEELNFNEG QLIQVLRKDQ DGDGFWEGIL DGKIGVFPSL
VVEELLSPEA AAAQALTSPD RPGPPPFNPP ELGMPAPPHL QLTRPTPSDE DLSVDLQGKT
KETEIEGEPE KEARENESKE NGEEGEKAEQ KEIEQKVERV EETPEAEKDE VEEEDLLPPP
PPPPPIEEEE EVGGDISEQV VTAEVHDGPE EQENPVAPPE DATKIENAEE KLTDENLTGE
STV
//
