ID R7V3T5_CAPTE Unreviewed; 409 AA.
AC R7V3T5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Mitochondrial-processing peptidase subunit alpha {ECO:0000256|ARBA:ARBA00016741};
DE AltName: Full=Alpha-MPP {ECO:0000256|ARBA:ARBA00030006};
GN ORFNames=CAPTEDRAFT_155657 {ECO:0000313|EMBL:ELU13518.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU13518.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU13518.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU13518.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP155657}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- FUNCTION: Substrate recognition and binding subunit of the essential
CC mitochondrial processing protease (MPP), which cleaves the
CC mitochondrial sequence off newly imported precursors proteins.
CC {ECO:0000256|ARBA:ARBA00002123}.
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DR EMBL; AMQN01018965; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQN01018966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB295146; ELU13518.1; -; Genomic_DNA.
DR AlphaFoldDB; R7V3T5; -.
DR STRING; 283909.R7V3T5; -.
DR EnsemblMetazoa; CapteT155657; CapteP155657; CapteG155657.
DR HOGENOM; CLU_009902_5_1_1; -.
DR OMA; LKYHHSP; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR PANTHER; PTHR11851:SF49; MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 20..102
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 113..314
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 409 AA; 45130 MW; 63D00B28929EB3A1 CRC64;
MSCHVRVFAA TEVSVTDHCA LLRPDTLIYA ASVNISGLPD VMNILSDVSL RPQITGPEIE
ESGLSIQWEI EALNMNPDPE PLLMEMIHTA SYSRNTLGLP KVTPLTNVPV IDKKLLYTFM
QNYHTPERMV VAGVGVDHQS LVDLTKKYFI TKKPIWEEDS SLIDKSRGQD LSISQFTGGE
HLVEKDLSNV SLGPTPMPEL AHVVIGLESC SHNDDDFVAF CVLNMLMGGG GSFSAGGPGK
GMYSRLYLNV LNRLHWIESA TAYNHAYADS GIFCIHASAH PSQLRDLTEV VTTELVRTAQ
MIGPSELMRA KTQLQSMLLM NLESRPVMFE DVARQVLARG HRLPATHYFD EIGSITAEDI
ERVAKRMLQS KPAVTALGSL NNMPSYTDIS KALSSNGKLP ALRKYSLFR
//
