ID   R7VCD7_CAPTE            Unreviewed;      1026 AA.
AC   R7VCD7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELU13981.1, ECO:0000313|EnsemblMetazoa:CapteP199134};
GN   ORFNames=CAPTEDRAFT_199134 {ECO:0000313|EMBL:ELU13981.1};
OS   Capitella teleta (Polychaete worm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC   Sedentaria; Scolecida; Capitellidae; Capitella.
OX   NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU13981.1};
RN   [1] {ECO:0000313|Proteomes:UP000014760}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA   Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA   Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA   Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA   Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA   Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL   Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ELU13981.1, ECO:0000313|Proteomes:UP000014760}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU13981.1,
RC   ECO:0000313|Proteomes:UP000014760};
RX   PubMed=23254933; DOI=10.1038/nature11696;
RA   Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA   Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA   Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA   Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA   Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT   "Insights into bilaterian evolution from three spiralian genomes.";
RL   Nature 493:526-531(2013).
RN   [3] {ECO:0000313|EnsemblMetazoa:CapteP199134}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
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DR   EMBL; AMQN01005005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KB294881; ELU13981.1; -; Genomic_DNA.
DR   AlphaFoldDB; R7VCD7; -.
DR   STRING; 283909.R7VCD7; -.
DR   EnsemblMetazoa; CapteT199134; CapteP199134; CapteG199134.
DR   HOGENOM; CLU_314296_0_0_1; -.
DR   Proteomes; UP000014760; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 2.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014760};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        41..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        902..925
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1026 AA;  115563 MW;  25030E3D26B7B05D CRC64;
     MCTLNTPRGR SFETNIRHKE EGLESGDTCN DNDEPCLQKK VIWSAILLVA VALMVFQVMN
     CVEKFLAYPS MTTFVLQPSD PVPLPAVTLC PSQPLRLTEV HKKGWYDILA DYSRDPKQKN
     ALSKLNKINV TSRVVYATGG HRIADVLVSC QSESGLCSTT SFSTTLTDNG ICFTHNFSSR
     GLRLLLNPAP YNQFNPHASN SPGCGFRAIF HGTQAFPADT HGSLLLPNGY HSEVQLLGQR
     VKLLAPPNGQ CVNSATPISE CAMTCRANDI AGKCGCQPYW MSAKDNSSIC NMRRHLTCAL
     QSLGMSFGLL CNSDCNSFKG TDAECNCPSP CLSHKYQGTL SLSQLTDTTY DQSESKINQL
     SVQEDIHAAE NIRARFTPEV LNTDKAQLNK VTRTLDDVIV SFETFRGNLG DSAQSVRRTV
     DELQPRVKFH LHNALGGLRR TLEHGFIGAW DEVEDKFLKP LANGFHEVMS AYDRSIKQLR
     FTSTSETIMR KVIFYSTDSE LSGKLEIAIQ ALDNLTKVYY SLLNAEPIVS YAVTPERRYD
     ASLVPFEVLS HYGEQLKMYY NGLSENIAGF IEDCLALKNV LKDVHGTNTL NETANSVAKA
     KFVEHSRQIN AFLVLFRSKI IDKARETIDE KIERMKKMNH TMMSLANDIL QETALREHIV
     NSRYISAYSN LVIFAQKAQL YTSKDAVTKS ALAETGLMKS NVDAFMELEG IYGEIADKTN
     ELGDMWRKFK AVVSSLWRTF LSDTSVRDFY FQLYNDVTDM INHPVKIQHF KEIFTHSKML
     DISAEDSVRI QPREYYELLN ADVAVIDMDT QIDDVDKLFA KWTTRTDLSI VAKGSVGQLL
     QSFKDLKSNL EDYRRRTTFG KKYFRENFIE LHVTMPEVST SEVVQTSAYS LEMLLRDIGI
     ALLLYLGASL LTFVEFIDVL LSCICRRDTK KKNKRMHRRS PDMPSSVRGT PVIQYETISQ
     QPPKDMLYHS HPVPSHNHVH TKPPDLQYVH SRTLDSGNGN GMMTLPAARK YKEIPPPRVH
     FANTDI
//