ID R7VKZ0_CAPTE Unreviewed; 1026 AA.
AC R7VKZ0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 13-SEP-2023, entry version 54.
DE RecName: Full=Formin-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CAPTEDRAFT_171809 {ECO:0000313|EMBL:ELU17806.1};
OS Capitella teleta (Polychaete worm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Polychaeta;
OC Sedentaria; Scolecida; Capitellidae; Capitella.
OX NCBI_TaxID=283909 {ECO:0000313|EMBL:ELU17806.1};
RN [1] {ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|Proteomes:UP000014760};
RA Hellsten U., Grimwood J., Chapman J.A., Shapiro H., Aerts A., Otillar R.P.,
RA Terry A.Y., Boore J.L., Simakov O., Marletaz F., Cho S.-J.,
RA Edsinger-Gonzales E., Havlak P., Kuo D.-H., Larsson T., Lv J., Arendt D.,
RA Savage R., Osoegawa K., de Jong P., Lindberg D.R., Seaver E.C.,
RA Weisblat D.A., Putnam N.H., Grigoriev I.V., Rokhsar D.S.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ELU17806.1, ECO:0000313|Proteomes:UP000014760}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=I ESC-2004 {ECO:0000313|EMBL:ELU17806.1,
RC ECO:0000313|Proteomes:UP000014760};
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
RN [3] {ECO:0000313|EnsemblMetazoa:CapteP171809}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the formin homology family.
CC {ECO:0000256|ARBA:ARBA00023449}.
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DR EMBL; AMQN01003939; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AMQN01003940; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB292298; ELU17806.1; -; Genomic_DNA.
DR AlphaFoldDB; R7VKZ0; -.
DR STRING; 283909.R7VKZ0; -.
DR EnsemblMetazoa; CapteT171809; CapteP171809; CapteG171809.
DR HOGENOM; CLU_003597_0_0_1; -.
DR OMA; MMPGFSP; -.
DR Proteomes; UP000014760; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0022604; P:regulation of cell morphogenesis; IEA:InterPro.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR043592; FMNL_animal.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR45857; FORMIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR45857:SF4; FORMIN-LIKE PROTEIN; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 2.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000014760}.
FT DOMAIN 5..469
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 527..926
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 977..1011
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 439..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 919..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1000..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..514
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..943
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1026 AA; 117142 MW; 51E953224DC0AFE4 CRC64;
MSRVPKPTDP RELDRRFNKV LVSSMDLPPD KVKLLRGYDE EKKWDLICDQ DRVSAKNPPS
FYLTKLKVYL DPSASKSSKV RDLLSKRRML GDSTSTQTLR DLEISLRTNH IEWVREFLGE
GHMGLDVLID YLSFTQLVMR TEQLDCSPDN PDASMLNNGV EKGGTLKGRQ SIFGGNSTPA
QKRVSRMKPS HSKLNFGDAT DDVHVCIMCL RAIMNHQYGF NLVFAHKQAI NSIALSLNHK
SLRTKALVLE LLAAVCLVSG GHEIILNAFD NFKEACSEIH RFQTLMYYFR HYEDFHIDFM
VACMQFINIV VHSVEDMNFR VHLQHEFTLL GLNEYLEQKL RSTESDRLAI QVNAYLDNTV
DVATLLEDSD TKTAALEKVA ELEDDLAFAN ERMQEMEEEA LEKIAQLETN ILESTEENSQ
LKTLAENQET ELRNLQQMLT TKDEESQRRV SQLETRLQDM ESMKHKVTSP VKTPPSAVPP
PPAPAPPPPP CAPPPPRPPS AVPPPPPPMG APGVPALPGT TMGAMTIKRK LATKYRLPIL
NWVAMKPNQV KGTVFSELDD EKLYETLDFN QFEEAFKLNT AGSLGADDLE TPTLNKRKMS
RRPETISLLD NNRLRNVAIT RRKIELQDDD VVKAINSLNL QTLSLERVEI LQRVMPNEQE
VKAFKEYTRD HKPVEVLSDE DKFMMSLMKV ERLPQKLTIM SFIGNFFDTY HHLQPQLNAI
IAASKSIRNS RKMRKLLEII LAFGNYMNSA KRGGVYGFRL QSLDMLLDAK SSDKKMTLLH
FIVQTVQTKF PELMNFDKEL GFVEKAATVS MENVLADIND LSKGMELTLR EFELRSRDRE
PPTILLDFIK NSEDKMKKLK TDSKSAQDAY QDVVEFFGEN TKTLAPNVFF ALFVRFSKSF
KQAVQDIEVM RKLEERPPMG SFREKKSNTL PAPKNSSVRI TRPRPPNNIC TIFKDAVVNE
LRKKQRLIKE KKVLNRDEVY HGALEDILLD LKNEPYRRAD AVRRSQRKKA DNIQPAPKDI
VANSRF
//
