ID R7YXG7_CONA1 Unreviewed; 737 AA.
AC R7YXG7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DUF803-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=W97_05851 {ECO:0000313|EMBL:EON66605.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON66605.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH767581; EON66605.1; -; Genomic_DNA.
DR RefSeq; XP_007781922.1; XM_007783732.1.
DR AlphaFoldDB; R7YXG7; -.
DR GeneID; 19903162; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_012349_2_1_1; -.
DR OMA; HEIWGAI; -.
DR OrthoDB; 2906343at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF93; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 60..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..89
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..487
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 78257 MW; AE9A13C73932CE65 CRC64;
MIIPYHQNIA VTAIAPSAHL PGLGDTEGWS SLIGIVTAII GNVLISFALN TQRYAHIKLS
QERDARRRQR RAGQSRNHGS AGYGTQQSQI AEERAKRNLG AKYDAQGVHM MHDEDVTETD
VLIPKLGSGS SSDSEDATAQ KEQSGSEGRK KSYLKSPYWW IGIVLMTVGE AGNFLAYGFA
PASIVSPLGV VALISNCMIA PFMLGERFRK RDLLGVAIAV AGAVTVVLSA KDSNPKLGPD
EIWHLIATWE FETYLGITTV CIVGLMIASK KYGEKSIFID LGLVGLFGAY TALSTKGVAS
LLTYTIWRAL TFPVTYLLLA VLIGTAVMQI KYVNRALQRF DATQVIPTQF VLFTLSVILG
SAVLYRDFER TTASDAGKFI GGCALTFLGV WFITTARPRH EDEDDRAPED DDAIDLVDDE
YENVSQDSPS RRSGKRPSLA ALQTRSTSSH ARRLSYPRYS RAGETPTSQD EPSSRLDHSA
SGPQSPAVPS APQTPSEPQS TSAFLSPVTN LRSAPPHQRL QQPEQQRRPQ AAPLLYPTLS
APVLPSEAQA LSPRPGTPRK TSELLSPYPP VTPLAPAAAD ARGAAAVAPG SASVLRARNS
IAGMLPGPLM SPLSASLSAV VADSLRRGVG GGGARRRRRL SEAGKSMGGG GGGEGMEGWA
GRGVRSDADV LAGNSGEGGS GGELTSEGGD PGATATATGS RGRSLSGVLG DVLKGFRRER
EAQDEEVAGR RRAGEEE
//
