ID R7YZD0_CONA1 Unreviewed; 619 AA.
AC R7YZD0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Mitochondrial import inner membrane translocase subunit TIM50 {ECO:0000256|ARBA:ARBA00020799};
DE AltName: Full=Mitochondrial import inner membrane translocase subunit tim50 {ECO:0000256|ARBA:ARBA00013483};
GN ORFNames=W97_06520 {ECO:0000313|EMBL:EON67267.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON67267.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004434}.
CC -!- SIMILARITY: Belongs to the TIM50 family.
CC {ECO:0000256|ARBA:ARBA00006344}.
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DR EMBL; JH767586; EON67267.1; -; Genomic_DNA.
DR RefSeq; XP_007782584.1; XM_007784394.1.
DR AlphaFoldDB; R7YZD0; -.
DR STRING; 1168221.R7YZD0; -.
DR GeneID; 19903831; -.
DR eggNOG; KOG2832; Eukaryota.
DR HOGENOM; CLU_023309_0_0_1; -.
DR OMA; DTHAPHA; -.
DR OrthoDB; 11362at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd07521; HAD_FCP1-like; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR004274; FCP1_dom.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR PANTHER; PTHR12210; DULLARD PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR12210:SF3; MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50; 1.
DR Pfam; PF03031; NIF; 1.
DR SMART; SM00577; CPDc; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS50969; FCP1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00022792};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
FT DOMAIN 326..469
FT /note="FCP1 homology"
FT /evidence="ECO:0000259|PROSITE:PS50969"
FT REGION 30..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..144
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 67643 MW; BFC93B08AFFB3223 CRC64;
MLARAASRLL VPRALAFPAT RAATAQSIRT FKLNKQQPPA KKPSPPKSSP NVRPSRGPEV
PKDLTWKRND PIKFAAAGAA AAGSGAASSS ATPTTDAPAS PEQTGFSTSD NVESTTEPQA
PSEPVIIAMP PPTNQQPIEM PPPSDTPQNA QADTASSQEP VGAVPPVEPS LEDTPRPSQP
LPDLRQGIPS TFEAEFLKPV APEEPPSVSK APGNDVNLTD DPREPASAGS GGRGTGELPK
SAYETSSDRR RNRIANYSYA AMALAAVTGT LYLGREWEDE AEKNAYPDIP SGWSPSSIYQ
RATARLSGQM GYYTEPTFPK LLPAVDPAPP YTLVLSLEDL MVHSEWTREH GWRTAKRPGI
DYFLRYLSQY YELVIFTSLP SASADPIIRK LDPFHIIMWP LFREATKYEK GEYIKDLSYL
NRDLSKVILI DTKPSHAKLQ PENSIILPPW KGEPANKDLV ALIPLLEYIA TMGIADVRTV
IKSFEGKPIA QEFARREAKA REAFQKALAE EKAKRPKHSG TGWLLGALGM KPQAGAQAGG
LVIGDQSAAE GFEQGKMLSD QIRERGQKQY EAMEKEIREN GEKWLKEMEM EEKKAQEEQL
KSMKSGFTSW FGSGRSKAA
//
