ID   R7Z0J2_CONA1            Unreviewed;       542 AA.
AC   R7Z0J2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=W97_06927 {ECO:0000313|EMBL:EON67559.1};
OS   Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Coniosporium.
OX   NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON67559.1, ECO:0000313|Proteomes:UP000016924};
RN   [1] {ECO:0000313|Proteomes:UP000016924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Coniosporium apollinis CBS 100218.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   EMBL; JH767588; EON67559.1; -; Genomic_DNA.
DR   RefSeq; XP_007782876.1; XM_007784686.1.
DR   AlphaFoldDB; R7Z0J2; -.
DR   STRING; 1168221.R7Z0J2; -.
DR   ESTHER; cona1-r7z0j2; Fungal_carboxylesterase_lipase.
DR   GeneID; 19904238; -.
DR   eggNOG; KOG1516; Eukaryota.
DR   HOGENOM; CLU_006586_17_1_1; -.
DR   OMA; RIMLGEC; -.
DR   OrthoDB; 1552062at2759; -.
DR   Proteomes; UP000016924; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF4; CARBOXYLIC ESTER HYDROLASE; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT   DOMAIN          14..487
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   542 AA;  60447 MW;  5C6CC87B0CC79AF7 CRC64;
     MTKVTEPFFL DLDYRGHIEG LTIKDKSTGE PLCHYFGGIP YALPPLGPFR WRKPRSLPPC
     YRYGTRASPG IYTTAAGLCP QPGFGKKLNT KAWDEDCLQC NVWLPAGKAS EKGWPVFFYI
     HGGFLQFGSP NGMDPSALLS ETDCKCIIVM PAYRLNVFGF LASRELQQEA GHEAYAGNLG
     FWDQRLALEW TYKNISYFGG DASNITVGGY SAGAHSAFHQ LAHELYYPSQ PPIIRHVIMW
     SNGPGLQPKS LQEVQNQFDE LLQHLHIPLT LPSSEKLSRL RTLPAKSLIA ATLKMTHHQF
     RAVTDNSFVR ASLFTDIDSG AFAARMRDRG IKLMLGECAD EHFVYGAWRP PVQNTLAGLH
     TRLLADYPHA AVDALLKHYF PTGTLPPGWK DWRDAFGRVY ADTQIHTLQR GFVAALARGG
     VGELVYRYRI EWRAGCVDGM APREWGVTHG TDLAGWFWGN GIGGGLMKEE KRVVEVAFVG
     PLGQFARGEE MEWGTKSIRD VRRLRSDGVV DVWVDERWDE GIQVWEDLKA VGSTAASPAA
     KL
//