ID   R7Z1F5_CONA1            Unreviewed;       933 AA.
AC   R7Z1F5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=PRP1 splicing factor N-terminal domain-containing protein {ECO:0000259|Pfam:PF06424};
GN   ORFNames=W97_07420 {ECO:0000313|EMBL:EON67923.1};
OS   Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Coniosporium.
OX   NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON67923.1, ECO:0000313|Proteomes:UP000016924};
RN   [1] {ECO:0000313|Proteomes:UP000016924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Coniosporium apollinis CBS 100218.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Associated with the spliceosome.
CC       {ECO:0000256|ARBA:ARBA00011524}.
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DR   EMBL; JH767591; EON67923.1; -; Genomic_DNA.
DR   RefSeq; XP_007783240.1; XM_007785050.1.
DR   AlphaFoldDB; R7Z1F5; -.
DR   STRING; 1168221.R7Z1F5; -.
DR   GeneID; 19904731; -.
DR   eggNOG; KOG0495; Eukaryota.
DR   HOGENOM; CLU_007010_0_0_1; -.
DR   OMA; DGWAWYY; -.
DR   OrthoDB; 655233at2759; -.
DR   Proteomes; UP000016924; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR010491; PRP1_N.
DR   InterPro; IPR045075; Syf1-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR   PANTHER; PTHR11246:SF1; PRE-MRNA-PROCESSING FACTOR 6; 1.
DR   Pfam; PF06424; PRP1_N; 1.
DR   Pfam; PF13432; TPR_16; 2.
DR   Pfam; PF13181; TPR_8; 1.
DR   SMART; SM00386; HAT; 11.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF48452; TPR-like; 4.
PE   4: Predicted;
KW   mRNA processing {ECO:0000256|ARBA:ARBA00023187};
KW   mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016924};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          12..169
FT                   /note="PRP1 splicing factor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06424"
FT   REGION          1..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..135
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   933 AA;  104677 MW;  F25D2CC3E4D2ADF0 CRC64;
     MTGRKDFLSQ PAPENYVAGL GRGATGFTTR SDLGPAREGP SEEQIKEALA KRAAQLGQAP
     PTAYGATGKK DDDDDDERFQ DPENEVGLFA NGTYDRDDDE ADRIYQDVDE RMDRRRKARR
     EAREQKEREE YERNNPKIQQ QFADLKRALG SVTDEDWANI PEVGDLTGKN RRAKQELRKR
     FYAVPDSVIA GARDATQFDT SISADGPDGA GTSADNADGN MTNFAHLQAA KDKVLQVRLD
     QAAQAPGMDS VAGTATNIDP KGYLTSLSKS ELKAGEVPVG DINRARELLE SVARSNPKHG
     PAWIALARLE EFAGKIVKAR QIIAEGCARC PTSEDCWLEN IRLNDNHNAK VIAANAIKAL
     PRSTRLWTTA MNLETDTRAK KRVLRQALDH IPQSVQLWRE AVNLEEDPAD ARLLLAKATE
     VIPLATELWL ALARLETPEN ARAVLNKARK AVGGQGDSHL IWVAASRLEE ALGNTAMVYK
     VMERGVKTLA RESAMLKREE WIAQAEKCEE EGAVITCGAI IRETLGWGLD EDDDRKDIWM
     DDAKDSIARG KYETARAIYA YALRLFYNKK SVWRAAIDLE RNHGTREALW QLLEKAVEAC
     PHEDFWMDLA KSKWQAGQTD EARRVLKRAF DMSSSENIWL FAVQMEADNG QIDRARQLLT
     AALEKAGTDR VYVKFVAFER QQGNIDAALD LVTRGLELYP HNAKLHMQKG QIYESLNKLP
     AAREAYAAGI RACPKSVPLY LLAARLEEKA GVTVKARSIL DRARLQVPKN AEILTERVRL
     ERRAGNLQAA NNLMAQALQE LPTSGLLYSE KIMHLEARTH RKPRALEAIK RVENDAYLFV
     TIARIFWGER RLEKAMSWFE KAILLDADLG DTWAWYYKFL LQHGTDEKRE EVVAKCVLAE
     PRHGEVWQAV AKDPKNAGKG REEILKMVVQ RLE
//