ID R7Z266_CONA1 Unreviewed; 1172 AA.
AC R7Z266;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Cep57 centrosome microtubule-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=W97_07252 {ECO:0000313|EMBL:EON68104.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON68104.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH767593; EON68104.1; -; Genomic_DNA.
DR RefSeq; XP_007783421.1; XM_007785231.1.
DR AlphaFoldDB; R7Z266; -.
DR STRING; 1168221.R7Z266; -.
DR GeneID; 19904563; -.
DR eggNOG; ENOG502S3TV; Eukaryota.
DR HOGENOM; CLU_004834_0_0_1; -.
DR OMA; MKSDQIY; -.
DR OrthoDB; 2729811at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR InterPro; IPR024957; Cep57_MT-bd_dom.
DR InterPro; IPR025925; PPC89_CLD.
DR PANTHER; PTHR19336:SF9; SPINDLE POLE BODY PROTEIN PPC89; 1.
DR PANTHER; PTHR19336; UNCHARACTERIZED DUF1167; 1.
DR Pfam; PF14197; Cep57_CLD_2; 1.
DR Pfam; PF06657; Cep57_MT_bd; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT DOMAIN 410..475
FT /note="PPC89 centrosome localisation"
FT /evidence="ECO:0000259|Pfam:PF14197"
FT DOMAIN 1011..1087
FT /note="Cep57 centrosome microtubule-binding"
FT /evidence="ECO:0000259|Pfam:PF06657"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 90..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 185..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..825
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 982..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1145..1172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 456..490
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..703
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..762
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..805
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..825
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 863..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..939
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1172 AA; 130706 MW; A0C4A72B2E62631B CRC64;
MSRDLSASRL SIPSPTKSLH DSEPAQPTLS SLDSQNEDLL QSTQQLDVTA TQQLPGMRTT
AKKFGFYNPP KPEYHVNTSA LDAFQDFTAA SPSEEDSMSI EVGRGVKKSG SARSTPNRYD
RDMSPNILLS VEDNSLYEVT ATPPVRPRPT ARKSDGFERG NLRRDAQIRR ASSLGQKEID
AMLARSSKAG ERVSPGKGAS QRRRTTLAQM HTRISGEEAE VALERPPTVT MTAKTTRFGN
PRSRQTSAAL NSTSGTPQRA AAATPANVTA QSFMLPDLPN LTELVSGVYK DGTPVFSRSA
KARSRFVSDS YPRRNGGGQP SYSAVESIPV PADEKAIFAS LQLLKEKVAQ LEQEKAESDK
KIEDYENEVA DMKAELSAQE NMRRSDSALG ASDAEGGREK TNWRIEKMRL ESSVHSLQTR
LDRAERKVSV SEIATKRATQ ERDNLVTQLS TAFYTTEELK AEKEALQSEN EHLRNEVDEL
RSENETLRAE LVQNAAYFED ETQQLQKRME RKDHGFQREN ETLRAELARA HAQHDDQTQQ
WNRKELETRR QKAEYNKLKS ENDRLKSQLA QAKAQREEEA RRAKIQQAEF QARLDQRDDT
IRQFQDMPQE DVNSTLRHEN EDLRVQLAQL NAQHDDETQQ WGQKESQLRS RIERKEAALR
EQRELNQEIL ESKQPAYHER TAPNETRADE AIKETETVKS NGKKRTGGRV GQDTQARISD
KVDLEVRNSR SVSGAKPSKT EPPAQSRTKS RSKSRDHSLR PSTSQDAKFL RRDPVPASPA
EPVVSHDLSD AESTTDLEIR PKSTTRSARE VTNVTNDVPA EDTSAADLTY LSSINRDELA
KIRRALEEER VATRRKATQA RQQKNETIRS SASLPRKSSL KDLTGRSDPV DDHTQQSGPA
DHNNNIESDT DSQLSSDEED ASAPQAKQNT SNSILSHSAR RPRSAPELTS AFILPDITLH
QRKVSISAHH DAAHDRKNCT VCHRGDSSST QPVAIPTPVP VSDRMPDDVD ATMRPAQPPA
LALATVIKEL QDELDHIKIE IATWETCLQG LDPSLGLRKR KKAQEELDAL LKAHDVKADQ
IYALHDVLEG QKAAAAAAGD AGGDGQADEV MGEKEVEETL MSVGIDPEEV RERMGRVKGK
KVTIRSHVSE EEESDEELPW EGINDTESLR GL
//
