ID   R7Z607_CONA1            Unreviewed;       606 AA.
AC   R7Z607;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   13-SEP-2023, entry version 45.
DE   RecName: Full=Thioredoxin {ECO:0008006|Google:ProtNLM};
GN   ORFNames=W97_08855 {ECO:0000313|EMBL:EON69595.1};
OS   Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Coniosporium.
OX   NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON69595.1, ECO:0000313|Proteomes:UP000016924};
RN   [1] {ECO:0000313|Proteomes:UP000016924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Coniosporium apollinis CBS 100218.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DeSI family.
CC       {ECO:0000256|ARBA:ARBA00008140}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH767618; EON69595.1; -; Genomic_DNA.
DR   RefSeq; XP_007784912.1; XM_007786722.1.
DR   AlphaFoldDB; R7Z607; -.
DR   STRING; 1168221.R7Z607; -.
DR   GeneID; 19906166; -.
DR   eggNOG; KOG0324; Eukaryota.
DR   eggNOG; KOG0907; Eukaryota.
DR   HOGENOM; CLU_033441_0_0_1; -.
DR   OMA; VTLQMAC; -.
DR   OrthoDB; 151499at2759; -.
DR   Proteomes; UP000016924; Unassembled WGS sequence.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   CDD; cd02947; TRX_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.90.1720.30; PPPDE domains; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR008580; PPPDE_dom.
DR   InterPro; IPR042266; PPPDE_sf.
DR   InterPro; IPR013535; PUL_dom.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR12378; DESUMOYLATING ISOPEPTIDASE; 1.
DR   PANTHER; PTHR12378:SF7; DESUMOYLATING ISOPEPTIDASE 1; 1.
DR   Pfam; PF05903; Peptidase_C97; 1.
DR   Pfam; PF08324; PUL; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SMART; SM01179; DUF862; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51858; PPPDE; 1.
DR   PROSITE; PS51396; PUL; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT   DOMAIN          1..141
FT                   /note="PPPDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51858"
FT   DOMAIN          151..308
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
FT   DOMAIN          309..601
FT                   /note="PUL"
FT                   /evidence="ECO:0000259|PROSITE:PS51396"
FT   REGION          165..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        166..187
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   606 AA;  65420 MW;  3E99923B9B99583E CRC64;
     MDVELYVYDL SKGMARQMSR QFLGIHIGAV YHTAVVFGGV EYFFGAGVQT CYPGTTHHGA
     PMEIIPLGRT DLPLDVILEY LESLKQIYTR ESYDLFLHNC NNFSNDFAMF LVGRGIPDHI
     TSLPRTVLNT PFGAMLRTQI DSSMRSITQA PVPSRQVPPV KAATARVTNG ASNGTSSRIS
     NGTSTNGVPK TASAASFAPG EVHYATTIEK VDKLLASAKE KCAIIFFTSS TCAPCKIVYP
     AYDQLAAEAG DKAVFIKIDL NSSDPQIASR YSVRATPTFI TLLRGIKQEQ WSGANEAQLR
     GNVQLLLSAA FPPHPHSSLN LTHFHRASLR PELFTRIPPL DKLTAKLGKA ANDSAVLAVR
     SFISTRQSSG AIEAPPPDLP AFGAFLRRAT EELPAEVLFA AYDLLRVSLV DARVAGFFAE
     EAEARTLRCL VGHVNALGQG CPYNLRIVTL QLSCNLFASP LFRKFLLADA EVSELLTTLV
     ASSLLDSQHV NVRVAAMSLA LNLASAAHRV RMEEKREALP ESAAVELVAS VLEALAVEQE
     SKEVVRGLVL ALGFLVYMAP EGGEVLDLCK VMDAEGTVRG KEGLSGGDAV VKEVGREMLG
     KGLRTK
//