ID R7ZF16_LYSSH Unreviewed; 250 AA.
AC R7ZF16;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:EON72589.1};
GN ORFNames=H131_10628 {ECO:0000313|EMBL:EON72589.1};
OS Lysinibacillus sphaericus OT4b.31.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX NCBI_TaxID=1285586 {ECO:0000313|EMBL:EON72589.1, ECO:0000313|Proteomes:UP000013911};
RN [1] {ECO:0000313|EMBL:EON72589.1, ECO:0000313|Proteomes:UP000013911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT4b.31 {ECO:0000313|EMBL:EON72589.1,
RC ECO:0000313|Proteomes:UP000013911};
RA Pena-Montenegro T.D., Dussan J.;
RT "Draft genome of the heavy metal tolerant bacterium Lysinibacillus
RT sphaericus strain OT4b.31.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON72589.1}.
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DR EMBL; AQPX01000017; EON72589.1; -; Genomic_DNA.
DR RefSeq; WP_010859074.1; NZ_KB933398.1.
DR AlphaFoldDB; R7ZF16; -.
DR PATRIC; fig|1285586.5.peg.2154; -.
DR eggNOG; COG1414; Bacteria.
DR HOGENOM; CLU_062618_4_3_9; -.
DR OrthoDB; 9791752at2; -.
DR Proteomes; UP000013911; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..65
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 66..249
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 250 AA; 28857 MW; 73D37E703C14C442 CRC64;
MTVKTLKNSL DILECFASTE NALGVREISR MTNMHTSVVQ RTINTFTEAG YLIQDEGTKK
YKMGYKMFIF YDVLSHSNDP HSTIYELMQN LASEINESVF LTYMDNEYGV TTKIAESNKN
IKYAVSLGTK TPLYIGASCK VMFAYLDEEK QLELLAHFNK EQSQEEHKQL LAHLKNELQI
IRQHNWCMTV GEYNEHAFGI SVPLFNKKKE IMASLTISGL IYDMNEQREK YMLAQLLQVS
HQIQSHITKL
//
