ID R8APX2_PLESH Unreviewed; 335 AA.
AC R8APX2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Zinc transport protein ZntB {ECO:0000256|HAMAP-Rule:MF_01565};
GN Name=zntB {ECO:0000256|HAMAP-Rule:MF_01565,
GN ECO:0000313|EMBL:EON88369.1};
GN ORFNames=PLESHI_10880 {ECO:0000313|EMBL:EON88369.1};
OS Plesiomonas shigelloides 302-73.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Plesiomonas.
OX NCBI_TaxID=1315976 {ECO:0000313|EMBL:EON88369.1, ECO:0000313|Proteomes:UP000014012};
RN [1] {ECO:0000313|EMBL:EON88369.1, ECO:0000313|Proteomes:UP000014012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=302-73 {ECO:0000313|EMBL:EON88369.1,
RC ECO:0000313|Proteomes:UP000014012};
RX PubMed=23814109;
RA Pique N., Aquilini E., Alioto T., Minana-Galbis D., Tomas J.M.;
RT "Genome Sequence of Plesiomonas shigelloides Strain 302-73 (Serotype O1).";
RL Genome Announc. 1:e00404-13(2013).
CC -!- FUNCTION: Zinc transporter. Acts as a Zn(2+):proton symporter, which
CC likely mediates zinc ion uptake. {ECO:0000256|HAMAP-Rule:MF_01565}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H(+)(out) + Zn(2+)(out) = H(+)(in) + Zn(2+)(in);
CC Xref=Rhea:RHEA:71195, ChEBI:CHEBI:15378, ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01565};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_01565}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_01565}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|HAMAP-
CC Rule:MF_01565}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON88369.1}.
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DR EMBL; AQQO01000345; EON88369.1; -; Genomic_DNA.
DR AlphaFoldDB; R8APX2; -.
DR STRING; 703.SAMEA2665130_01679; -.
DR PATRIC; fig|1315976.3.peg.2037; -.
DR HOGENOM; CLU_007127_2_0_6; -.
DR OrthoDB; 9803484at2; -.
DR Proteomes; UP000014012; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd12833; ZntB-like_1; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR HAMAP; MF_01565; ZntB; 1.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR023714; Zn_transp_ZntB.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF3; ZINC TRANSPORT PROTEIN ZNTB; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_01565};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01565}; Ion transport {ECO:0000256|HAMAP-Rule:MF_01565};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01565};
KW Reference proteome {ECO:0000313|Proteomes:UP000014012};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01565};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01565}; Transport {ECO:0000256|HAMAP-Rule:MF_01565};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|HAMAP-Rule:MF_01565}.
FT TRANSMEM 276..297
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01565"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01565"
SQ SEQUENCE 335 AA; 37698 MW; 479A8B074F47F05A CRC64;
MQVNDVQVKG AISALWLDGQ GGALPIDKLA KANTTQAKDA KLSAEQGPVW LHLDYSQPDS
ANWIRDTALL PENVKEALLG ESSRPRFTRL GEGVLITLRS INYNNDERPD QMVALRAYVS
RDLIVSSRRR RLFSVEDLET ELWNGNGPTN SSEWVVEICD CMTDYASEFI DDLHEVIIEL
EDGLLEHKIP DRGRLALIRK QLIVLRRYLS PQRDVYSRIA AEKISWFDDD DKRRMQEVSE
RLGRTLDDLD AAISRTSVLA DEIANLLADA MNRRTYAMSL LAMMFLPISF LTGLFGVNLE
GIPGKGFAGS FPLFCLALVG LAGGIGFWLK RKRWL
//
