ID R8ARW3_PLESH Unreviewed; 867 AA.
AC R8ARW3;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=PLESHI_07935 {ECO:0000313|EMBL:EON89061.1};
OS Plesiomonas shigelloides 302-73.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Plesiomonas.
OX NCBI_TaxID=1315976 {ECO:0000313|EMBL:EON89061.1, ECO:0000313|Proteomes:UP000014012};
RN [1] {ECO:0000313|EMBL:EON89061.1, ECO:0000313|Proteomes:UP000014012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=302-73 {ECO:0000313|EMBL:EON89061.1,
RC ECO:0000313|Proteomes:UP000014012};
RX PubMed=23814109;
RA Pique N., Aquilini E., Alioto T., Minana-Galbis D., Tomas J.M.;
RT "Genome Sequence of Plesiomonas shigelloides Strain 302-73 (Serotype O1).";
RL Genome Announc. 1:e00404-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON89061.1}.
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DR EMBL; AQQO01000047; EON89061.1; -; Genomic_DNA.
DR RefSeq; WP_010863210.1; NZ_KB944508.1.
DR AlphaFoldDB; R8ARW3; -.
DR PATRIC; fig|1315976.3.peg.1567; -.
DR HOGENOM; CLU_000445_113_1_6; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000014012; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EON89061.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000014012};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 386..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 645..862
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 867 AA; 94974 MW; F02B898C16214709 CRC64;
MRDDVRADAL LASLENEQKG KLKVFLGAAP GVGKTYAMLQ AVREQFNEGT SILIGVVETH
GRRETLALLD KLPMQARKTV YHRNQRIEEM DLDALLEQKP ALAVVDELAH SNAPGSRHEK
RWQDVQELLA AGIDVYTTLN VQHLESLNDL VWQLTGVRVK ETLPDQVLLD ADSLVLIDLP
PKELLERLRE GKVYVPHQAK TALQSFFSLN NLTALRELAM QTAASHVEGD LQLQWQAAGK
ATQPLRGKLM VCLGTQQGMA LVRYGHRFAQ RRQLPWLVLH VDTNGQTSAE TEQALALASQ
LGAKVLTLSS PSVADAIRLT SEQQQVSQLL LGKPHKIPWR PSLVQYLIRA TQGLEITLVD
VAQTADAVSN PKRKDKLNAA GKWRDYAISA VIMGSTTVLA WFLSSWLPDS SIPLIFVLGV
MTTALSTSLL PATLASIFGF IAHNLLFVDP LYSLKVSRHS DLLTLLVLLI VGMTAGRLAS
RQRKQLISLR ESQHLGNALL ALNQALSKAN SSEEVVRLGS EAIAGALHIA VVVLDQDYLE
HSGNSLAIPG QTDKAAIDWC LAKKQSAGAF TATLNAAESQ YHPLTDHLVL GIRLLSPLSA
GAERQLQALL SDMRAALARI DLDERLADSQ LQAETDRMRA ALLSSVSHDL KTPLATIMGA
SGTLLAYDEK IPPEEKNELL QSIQEEAARL RSYVQNLLDM TRIGSPDFQL KREWVAIEDL
VDAAYHRLQA AWRQHKLLIH IDQNIPLLYV HGALIEQVLV NVFDNAVRYS PAGTPIEFKV
VLALPDIIID IIDMGAGIAD ADRSKIFNLF YTQPVGDCGS RGTGLGLAIS RAMIEAHGGK
IWAFPGVNKV GTCMRISLPV GLNSPEK
//
