ID R8AU47_PLESH Unreviewed; 676 AA.
AC R8AU47;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN ORFNames=PLESHI_03431 {ECO:0000313|EMBL:EON89848.1};
OS Plesiomonas shigelloides 302-73.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Plesiomonas.
OX NCBI_TaxID=1315976 {ECO:0000313|EMBL:EON89848.1, ECO:0000313|Proteomes:UP000014012};
RN [1] {ECO:0000313|EMBL:EON89848.1, ECO:0000313|Proteomes:UP000014012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=302-73 {ECO:0000313|EMBL:EON89848.1,
RC ECO:0000313|Proteomes:UP000014012};
RX PubMed=23814109;
RA Pique N., Aquilini E., Alioto T., Minana-Galbis D., Tomas J.M.;
RT "Genome Sequence of Plesiomonas shigelloides Strain 302-73 (Serotype O1).";
RL Genome Announc. 1:e00404-13(2013).
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. Type III
CC sulfatase family. {ECO:0000256|ARBA:ARBA00033751}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON89848.1}.
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DR EMBL; AQQO01000025; EON89848.1; -; Genomic_DNA.
DR RefSeq; WP_010862320.1; NZ_KB944507.1.
DR AlphaFoldDB; R8AU47; -.
DR PATRIC; fig|1315976.3.peg.662; -.
DR HOGENOM; CLU_014655_1_0_6; -.
DR OrthoDB; 9815874at2; -.
DR Proteomes; UP000014012; Unassembled WGS sequence.
DR GO; GO:0018741; F:linear primary-alkylsulfatase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0018909; P:dodecyl sulfate metabolic process; IEA:InterPro.
DR CDD; cd07710; arylsulfatase_Sdsa1-like_MBL-fold; 1.
DR Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR InterPro; IPR029229; Alkyl_sulf_C.
DR InterPro; IPR029228; Alkyl_sulf_dimr.
DR InterPro; IPR044097; Bds1/SdsA1_MBL-fold.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR PANTHER; PTHR43223:SF1; ALKYL_ARYL-SULFATASE BDS1; 1.
DR Pfam; PF14864; Alkyl_sulf_C; 1.
DR Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF55718; SCP-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014012};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..676
FT /note="Metallo-beta-lactamase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004462250"
FT DOMAIN 125..347
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 676 AA; 74186 MW; 9CCBB853A76D1235 CRC64;
MKLSPIALSL LVLSAPLTHA AQTSKDATPA TQQFLTQVAE TLPTSNIDDI AFATKGLIAQ
EKDLQIKNAA GKVVWELGSY DFLLKDAPST SATIHPSLLR QATLNMNHGL YKVTDGIYQV
RGYDLANITF VRGKTGWIVF DPLTVPETAK AAYDLVSKQL GKLPVVAVVY SHSHADHFGG
VKGIISQADV DSGKVQVIAP AGFTEHAISE NVLAGNAMAR RTTYQYGNML PKSEKGQVDA
AIGKGVALGE LSLITPTKEI SKDIEEITVD GVTMVMQSTP GTEAPAEMNT WLPQFKTYWA
AENTIGGLHN VYTLRGAPVR DPRAWSSYIN QSLHLFGDKA EVIMASHTWP RWGNDTIVSF
LEKQRDMYGF INNEALRLAN HGVTIDEVQD EFKVPESLAR EWYNRGYHGS YHRNAKAVIN
KYLGYSDMNP AKLLPLSPKD AAPRYVAAMG GIDKVIAEGK RAFDQGDFRW CAEVVNYAVF
AEPGNMPARF QQADCLEQLG YQSESAGERN SFLMGAYELR NGVPKGVATK TASPDLIAAM
PVTDFLDYLA VRLDGNKADQ AGYTLTMNIN LSDSNEKVLM QVKNGNLSHI KGYQDNKPDV
TMTINRAALA DFMLQKASLQ ELQQAGRVEI TGDANRLYQL GTYLDNFDFW FNIVTPNDHS
QYSHGLSGSK TSPINR
//
