ID   R8VU55_9CLOT            Unreviewed;       832 AA.
AC   R8VU55;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=PASTA domain-containing protein {ECO:0000259|PROSITE:PS51178};
GN   ORFNames=HMPREF1526_02554 {ECO:0000313|EMBL:EOQ35974.1};
OS   Butyricicoccus pullicaecorum 1.2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Butyricicoccus.
OX   NCBI_TaxID=1203606 {ECO:0000313|EMBL:EOQ35974.1, ECO:0000313|Proteomes:UP000013981};
RN   [1] {ECO:0000313|EMBL:EOQ35974.1, ECO:0000313|Proteomes:UP000013981}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1.2 {ECO:0000313|EMBL:EOQ35974.1,
RC   ECO:0000313|Proteomes:UP000013981};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Van Immerseel F., Eeckhaut V.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Butyricicoccus pullicaecorum 1.2.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOQ35974.1}.
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DR   EMBL; AQOB01000010; EOQ35974.1; -; Genomic_DNA.
DR   RefSeq; WP_016148670.1; NZ_KB976104.1.
DR   AlphaFoldDB; R8VU55; -.
DR   PATRIC; fig|1203606.4.peg.2525; -.
DR   eggNOG; COG0768; Bacteria.
DR   HOGENOM; CLU_009289_6_0_9; -.
DR   OrthoDB; 9804124at2; -.
DR   Proteomes; UP000013981; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   CDD; cd06577; PASTA_pknB; 1.
DR   Gene3D; 3.30.10.20; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005543; PASTA_dom.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03793; PASTA; 2.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SMART; SM00740; PASTA; 2.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
DR   SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 1.
DR   PROSITE; PS51178; PASTA; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013981};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          694..754
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
FT   DOMAIN          758..825
FT                   /note="PASTA"
FT                   /evidence="ECO:0000259|PROSITE:PS51178"
SQ   SEQUENCE   832 AA;  90688 MW;  1585F94004F1E909 CRC64;
     MPIKGPGKEM QRRMAALAAV ACTIGFSAVV VRLLWMQVYQ YDYYNTKANS LQTRDTILQP
     KRGTIYDSNM TELAVSASTE RVEIYPNMFL SSDNTNTKVL KIPVEEQQER VAQLLSDVLG
     VDYNTALQKA QMTDKHGLSI AFGVEKEVAD QLRAKMTEAK KAYDEDTKRI RANDGQGTYS
     DEAFIYSGIL GFVDDYRRYY PMGSFASQVI GFMNESENPT GQSGIELQYE SELAGSSGRV
     VRAANSAGGN LPVEAEQYVP AQDGNSIVLT IDSTIQEMLE KQLETALADN PQARGGVSGI
     VMDVKTGDIL ALAELPDFDP NTPRIINNEQ QIATMKSDLV ETLTEKGMDT NNLPSDEWFK
     SGGVNNLSES IANNEEYISI LDDLRVTALN DMWKIKPVTD MYEPGSVFKL LTVASAYEEQ
     AVGSNSTFFC GGSLRVDSET VINCHKRGGH GQQTLTQALM NSCNVAMMQI VSQLGADSFY
     EYFDAFGLLN RTGIDLPGER DSIEGIDMHT LESLQKTKST LMTASFGQRF KVSPIQMLST
     VCAIVDDGKL KTPHVVKEIL NADGTVKQSI ETEVKRQVIS ADTSAYMREA MEKVVSEGTG
     QNAYVAGYRI GGKTATSELS LPGTPTEDQR FTASFIGVAP MDDPQIAVLV IISDLPYEAT
     HGGGAIAAPV VGRVMNDVLP YIGVEPVYDE TEADRREVST PRIIDMTKDE AAAAAESAGL
     TYRFLGEGDT VSDQVPSAGQ KVPVDSQMII YLGDRTKTTE PVTVPNLVGR APEEVEAVLK
     NNNLYLRRTG VASSKYNWQT TAIKQNPAAG TKVSVGTVIE VEFSNTEGVN DR
//