ID R9ABX5_WALI9 Unreviewed; 765 AA.
AC R9ABX5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401};
GN ORFNames=J056_001669 {ECO:0000313|EMBL:EOQ99584.1};
OS Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOQ99584.1, ECO:0000313|Proteomes:UP000014064};
RN [1] {ECO:0000313|Proteomes:UP000014064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT ichthyophaga: haloadaptations present and absent.";
RL BMC Genomics 14:617-617(2013).
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116}.
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DR EMBL; KE007240; EOQ99584.1; -; Genomic_DNA.
DR RefSeq; XP_009269572.1; XM_009271297.1.
DR AlphaFoldDB; R9ABX5; -.
DR STRING; 1299270.R9ABX5; -.
DR GeneID; 20374621; -.
DR KEGG; wic:J056_001669; -.
DR eggNOG; KOG1968; Eukaryota.
DR HOGENOM; CLU_003574_1_0_1; -.
DR OMA; LICNERN; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000014064; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IEA:UniProt.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF37; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014064}.
FT DOMAIN 65..155
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..735
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 765 AA; 84542 MW; CE90BB5056DEF547 CRC64;
MAPKRKTVVI SDSDEDVPPP KQKNSPQKKS KSSASSSAPA SSFSYKDYLQ RPGPESLGSK
SIPEGAPGCL SGLTLVFTGE LDNVGRDSAV EAAKRYGAKV TAAPSGKTSY VILGREPGPK
KLQTIQDKGL KTLDEDGFCN LIATTSPSQD PSYLNKVKKD EAKVKKDAEE MEAIEKEQKA
KDKRSSKASS FESTSPNSQL WTVKYAPTQL KDICGNKGQV EKILNWLQNW QHQLQAGFPS
DNSKNDIKSK RALLVHGAPG IGKTTAAHLA AKIAGFSPLE LNASDVRSKK LIENTTNIDN
TSIDSFFGSN SETHPLNHST CLIFDECDGM SSGDRGGVGA MNTLIRKTRI PIICICNDKA
NPKMRPFQST CGDIVFRRPE ATQVRSRIMS ILHREKMKLD PVVVDQLVSG SQSDIRQVIN
MISTWKLLSS SMNFDQGKEL VQQNQKFTIQ TPWTVMSNLF SPHMFGATST STLGSKADYY
FHDHSLIPLF VQENYVKCNP AKARDSNNEK AEFKRMKYAS KAADAISDGD LVDSMIHGSQ
QQWGLMPLHA MNSTVRPASF MYGGFKSFGR DTISFPMWLG QYSKTNKNIR ALGEIQAKMR
VKVSGDRDEI RQYYYPTLWP RMFNPLTESV PDIDSVINLL DNYMLSKDDF DVMSELGVGD
LALEKTVKCI PTKNKTAFTR NYNNRDHPIA FSRGQVIKPS AAQIKAEVPD HEDVLDDEDD
NVVDVKEEED DENDDVTADK LVKQPKKPAA SKRGKASASR GKGSK
//
