ID   R9ACE7_WALI9            Unreviewed;       858 AA.
AC   R9ACE7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN   ORFNames=J056_001383 {ECO:0000313|EMBL:EOQ99841.1};
OS   Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC   Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX   NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOQ99841.1, ECO:0000313|Proteomes:UP000014064};
RN   [1] {ECO:0000313|Proteomes:UP000014064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX   PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA   Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT   "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT   ichthyophaga: haloadaptations present and absent.";
RL   BMC Genomics 14:617-617(2013).
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DR   EMBL; KE007238; EOQ99841.1; -; Genomic_DNA.
DR   RefSeq; XP_009269286.1; XM_009271011.1.
DR   AlphaFoldDB; R9ACE7; -.
DR   STRING; 1299270.R9ACE7; -.
DR   GeneID; 20374335; -.
DR   KEGG; wic:J056_001383; -.
DR   eggNOG; KOG4629; Eukaryota.
DR   HOGENOM; CLU_333232_0_0_1; -.
DR   OMA; PQMSESF; -.
DR   OrthoDB; 1362946at2759; -.
DR   Proteomes; UP000014064; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   PANTHER; PTHR31323; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR   PANTHER; PTHR31323:SF1; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        496..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        537..555
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          444..479
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          64..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          795..858
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        795..834
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   858 AA;  96030 MW;  46C08706BA867F3F CRC64;
     MKSVNFHKGA GTQDTDTEDD DQLQPQSHSH SGVTLYDTPV SPVHATFPSS PYMSLHSDLD
     KPGFDSSTTN LTHAHSHGEK SPFELSDVPL GDSNDGNFHP PRPAYKKHAN RSFDALRNGE
     WSKYNASESK HNRFQFAEGD IPKSKVVRLY FFLINTSIIT RWAIFVIPIA GLLAIPLIIS
     VTAAPDAEIL RVRLLWWSIW LETIWVGWWA SWATSKIIPW FARHTIAVIL PNGKHMIDYF
     VRCEKYLAAV GWTVAVWAVF NFLVLVKFSR DHSDPSYSTL SVIAQVHAGI IICAAILAGE
     KIVIQLIAYN FHRTSYDDRI REQKFQVKVL AALYARSRDL GRKDTLDGFG KRGKEKGGVK
     AGRVFRKAAR EAKEAAANAT SALGNVASEI AGSSVLQPNS PISMVTNALA SGKKTRHLAR
     RIFYSFSPPY RTSLVLSDIA HFFPDPITAE EAFVVFDKEC NGDVTLEEIE MACLEIHRER
     LALTSSMRDL DSAVAALNKI LMSVYVVAAC LVIVAMLDVK FSTLVTSAGS LVLGMSWLIG
     TTAQEILASI IFLFVKHPYD VGDRVKIDGN DMTVKEMNLL YSIFRGIDGT ITQAPHAVLN
     LKYIHNYRRS GSTSEEFIFN VFYDTSFDQI EDLRSRMLHF LKTERRDFIQ ECDINILDLP
     DQEKMTLSTS INYKSNWQNI ALYTQRRVKW MVAMKIALAE SKIYGPAGDP LAPEPSLYMK
     VPYEPPAKTG DDVEAPLPDD ERTTDLRRAA SMALNGGRRA LIHRMDKEEE ALYQSGLETE
     PRENMVDTFT MQLPGGAQHS QHAQDAQHEG RPTTPHSTTQ SFNATPSQVE AGRVRIQSPE
     QIPGPPRGDS DYEMRRID
//