ID   R9AEE4_WALI9            Unreviewed;      1150 AA.
AC   R9AEE4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=Peroxisomal ATPase PEX6 {ECO:0000256|ARBA:ARBA00034811};
DE   AltName: Full=Peroxin-6 {ECO:0000256|ARBA:ARBA00034920};
GN   ORFNames=J056_000741 {ECO:0000313|EMBL:EOR00543.1};
OS   Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC   Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX   NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOR00543.1, ECO:0000313|Proteomes:UP000014064};
RN   [1] {ECO:0000313|Proteomes:UP000014064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX   PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA   Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT   "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT   ichthyophaga: haloadaptations present and absent.";
RL   BMC Genomics 14:617-617(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC         Evidence={ECO:0000256|ARBA:ARBA00034440};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC         Evidence={ECO:0000256|ARBA:ARBA00034440};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}. Peroxisome membrane
CC       {ECO:0000256|ARBA:ARBA00034691}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00034691}; Cytoplasmic side
CC       {ECO:0000256|ARBA:ARBA00034691}.
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DR   EMBL; KE007234; EOR00543.1; -; Genomic_DNA.
DR   RefSeq; XP_009268644.1; XM_009270369.1.
DR   AlphaFoldDB; R9AEE4; -.
DR   STRING; 1299270.R9AEE4; -.
DR   GeneID; 20373693; -.
DR   KEGG; wic:J056_000741; -.
DR   eggNOG; KOG0736; Eukaryota.
DR   HOGENOM; CLU_000688_0_0_1; -.
DR   OMA; DWAVASS; -.
DR   OrthoDB; 7477at2759; -.
DR   Proteomes; UP000014064; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
DR   CDD; cd19527; RecA-like_PEX6_r2; 1.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR003960; ATPase_AAA_CS.
DR   InterPro; IPR021463; Methyltransf_34.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047533; RecA-like_PEX6_r2.
DR   PANTHER; PTHR23077; AAA-FAMILY ATPASE; 1.
DR   PANTHER; PTHR23077:SF9; PEROXISOME ASSEMBLY FACTOR 2; 1.
DR   Pfam; PF00004; AAA; 2.
DR   Pfam; PF11312; Methyltransf_34; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00674; AAA; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Peroxisome {ECO:0000256|ARBA:ARBA00023140};
KW   Peroxisome biogenesis {ECO:0000256|ARBA:ARBA00022593};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014064}.
FT   DOMAIN          854..993
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
SQ   SEQUENCE   1150 AA;  127619 MW;  4E4887774C522215 CRC64;
     MISESPDREQ ALVDKFKKIT SSTITSRYFS SILQCLKRDL YNKNYLEAFG NDEYLDAYLA
     RYVPSRAIVY YRMMKEHSRL LGLRDGMRVN SIGGGAGSEL SGMQHLVEEI GLSDVQLSLI
     DIGKWDKVVN RLQTEFKDGV DVEFLNKNVL SDSSISYEGV DMITILFTIS ELFIQSKKST
     LQLLNKITEQ SKPGTKLVVA ESVGLSNIQV GGGGREYPLT MILDHTLQSK WNKHRSNVEL
     ELEEIYLHTA EALTQSDRED LVGRFIRRDA LYRINHKAYR PIHTQPFKTG VVGKRTRIFS
     VLTSGTFPVV DVDDDDDDDE ELNISHSFLH KSILSTPSAA SQLHLDVSLS PTTSSHQITI
     KPSHLAALEV YNGDWVLAQT TLSSPRLVQL QLSEQPLHSY SAQLSPLLLF NLNSGSNSPD
     SKLILKSINQ PIIPTASSVT ISRVSSPISL NKQYQQRFYA ALHHHFIVQP RLYKRGDLIE
     VDISDELVDK PRFEEDGENN EYNHPLKSSK KISKVWFKIT NLTASPPNDN LGAWVLPDQT
     EMVMLGVNQS YIPASAHQSP FKSYQEIQSL FKSAVKSFKL GLDMQLTLLI VGQSSSEALK
     AASSALGLHY LHLNCYDIAD DNQSQVIGSI QATIEKAASC LPLVVQFENI DALFSDSEDK
     KAGRVLSALK ECLEYLRSIS RSSSLPNIFT ATTNDSTNLA NECVSCFKHE VKIEAPKRSE
     RLEYIASILS NMQLSNDVSV AEIADQTASL FADDISNLIA RAQIIALERV MRMAKSLNCD
     IGDILSAGIT LSAEDIHLAL KQTKDNYASS IGAPSIPNVK WDDIGGLKDV KDEILDTVQL
     PLQKPELFAG GLKKRSGVLL FGPPGTGKTL LAKAVATECA LNFFSVKGPE LLNMYIGESE
     ANVRRIFQKA RDASPCVIFF DELDSVAPKR GNQGDSGGVM DRIVSQLLAE LDGMSSTNAQ
     VFVIGATNRP DLLDSALLRP GRFDRMIYLD VPSTHTAQAN ILAALTRKFK LEDRLDLLKD
     VTNRLPLNLT GADLYALCSD AMLKCMTRRV MKIENELKKI NDMSEGDFVA RYSSSHKRPI
     TPQYYLEFMA SSTDIDIVVS KADFSDAMAD LSPSVSQAEM ENYRKAQIKF TNVKKDNTKK
     DLGKGKARAD
//