ID   R9AKH7_WALI9            Unreviewed;       256 AA.
AC   R9AKH7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=peptide chain release factor N(5)-glutamine methyltransferase {ECO:0000256|ARBA:ARBA00012771};
DE            EC=2.1.1.297 {ECO:0000256|ARBA:ARBA00012771};
GN   ORFNames=J056_003266 {ECO:0000313|EMBL:EOR02704.1};
OS   Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC   Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX   NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOR02704.1, ECO:0000313|Proteomes:UP000014064};
RN   [1] {ECO:0000313|Proteomes:UP000014064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX   PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA   Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT   "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT   ichthyophaga: haloadaptations present and absent.";
RL   BMC Genomics 14:617-617(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-
CC         methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release
CC         factor] + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42896, Rhea:RHEA-
CC         COMP:10271, Rhea:RHEA-COMP:10272, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:61891; EC=2.1.1.297;
CC         Evidence={ECO:0000256|ARBA:ARBA00000932};
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DR   EMBL; KE007227; EOR02704.1; -; Genomic_DNA.
DR   RefSeq; XP_009266764.1; XM_009268489.1.
DR   AlphaFoldDB; R9AKH7; -.
DR   STRING; 1299270.R9AKH7; -.
DR   GeneID; 20376218; -.
DR   KEGG; wic:J056_003266; -.
DR   eggNOG; KOG2904; Eukaryota.
DR   HOGENOM; CLU_018398_0_2_1; -.
DR   OMA; CKLATIN; -.
DR   OrthoDB; 1121774at2759; -.
DR   Proteomes; UP000014064; Unassembled WGS sequence.
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR004556; HemK-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR007848; Small_mtfrase_dom.
DR   NCBIfam; TIGR00536; hemK_fam; 1.
DR   PANTHER; PTHR18895; HEMK METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR18895:SF74; MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE; 1.
DR   Pfam; PF05175; MTS; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EOR02704.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014064};
KW   Transferase {ECO:0000313|EMBL:EOR02704.1}.
FT   DOMAIN          74..171
FT                   /note="Methyltransferase small"
FT                   /evidence="ECO:0000259|Pfam:PF05175"
SQ   SEQUENCE   256 AA;  29092 MW;  DD6996ED7D022D56 CRC64;
     MVDSFGSADA YNEIRWVRQS CRSGKEAVFK LGQRLSGKPL QFVIGNQPFN SAVIQCIPPT
     LIPRQETEFW VDKLIARFCD NRQLRVLDLC TGSGCIGVSI AKELHCDSVV VVDSSPKACK
     LATINARNNL TKEQLERFEV KQMDILSESI DLSSYNVITI NPPYITQRDY KTLHSEVRDW
     EDKDALLAGG DEYGLVFYKR MIYLLKDAFN KQVWMEVGYN QAQLVVKLAK QSGVANVELI
     EDPFNDRINR VVILHL
//