ID R9AM76_WALI9 Unreviewed; 473 AA.
AC R9AM76;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Vacuolar amino acid transporter 5 {ECO:0000313|EMBL:EOR01206.1};
GN ORFNames=J056_004527 {ECO:0000313|EMBL:EOR01206.1};
OS Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOR01206.1, ECO:0000313|Proteomes:UP000014064};
RN [1] {ECO:0000313|Proteomes:UP000014064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT ichthyophaga: haloadaptations present and absent.";
RL BMC Genomics 14:617-617(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC {ECO:0000256|ARBA:ARBA00008066}.
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DR EMBL; KE007231; EOR01206.1; -; Genomic_DNA.
DR RefSeq; XP_009267997.1; XM_009269722.1.
DR AlphaFoldDB; R9AM76; -.
DR STRING; 1299270.R9AM76; -.
DR GeneID; 20377479; -.
DR KEGG; wic:J056_004527; -.
DR eggNOG; KOG1305; Eukaryota.
DR HOGENOM; CLU_009020_1_1_1; -.
DR OMA; DSIHHQR; -.
DR OrthoDB; 5485318at2759; -.
DR Proteomes; UP000014064; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR013057; AA_transpt_TM.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR PANTHER; PTHR22950:SF646; SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 10-RELATED; 1.
DR Pfam; PF01490; Aa_trans; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..465
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 52127 MW; 01C67A8E97B4C353 CRC64;
MSNSNQIRRI SRSNHSTQQP LLESNHRPRA LHTASIPSSV ANLANTIIGT GMLAMPSVIS
STGLIPAVIL ILLSSFLSSF GLYLLHLSST QLGSKRSSSF NAVANITYPN AAIYFDIAIA
LKCFGVAISY LLILGQLLPP LVTSFYHHLT PSHFEPPSVL LSRHFWISLF VVILSPLAHM
RHLNSLRYTS YISIFSATYL LMIVVLCAIH SPIPLPPPGN ITWAKFDSSA ISKFPVLVFA
FTCAQNFYPV KNELRSNSHG STCAVIAISI GIAAGLYQII GVLGYVTFGD KVNSNIMSMY
PDTSILISFG RLAIAVLVLS SYPLQVHPCR NSLDKIISSA KTTKPEWQQW EGDGDEHRDD
QVGDSDGEDA NDEFKIPPPS SPLRHSTLTV LILFFTWSIA MMVSQLDKVL AFVGSTGSTA
ISFILPGLFY RALSRNDTDP SRRWLRIGSR LLIIYGFSVM FFCLAFNFYD MFT
//
