ID R9AV50_WALI9 Unreviewed; 391 AA.
AC R9AV50;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=NIPA-like protein 2 {ECO:0000313|EMBL:EOR03976.1};
GN ORFNames=J056_002054 {ECO:0000313|EMBL:EOR03976.1};
OS Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOR03976.1, ECO:0000313|Proteomes:UP000014064};
RN [1] {ECO:0000313|Proteomes:UP000014064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT ichthyophaga: haloadaptations present and absent.";
RL BMC Genomics 14:617-617(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE007225; EOR03976.1; -; Genomic_DNA.
DR RefSeq; XP_009266193.1; XM_009267918.1.
DR AlphaFoldDB; R9AV50; -.
DR GeneID; 20375006; -.
DR KEGG; wic:J056_002054; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_012349_2_2_1; -.
DR OMA; HLQQSFI; -.
DR OrthoDB; 2906343at2759; -.
DR Proteomes; UP000014064; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF93; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 391 AA; 42640 MW; FAB47B165E3344E2 CRC64;
MKGNVAGVVA AIAGNVVIAL GLNIQKLSHL QISNLEENDD TLQYLRNGTF WVGLAMSSLG
ECCNFIAYGL SPAPLVAPLG SCALVANGIF SPILLQESFG LQEIAGSMLC ITGAFILVSS
NTAREDNVDY NTLITAINRP WFQTYLFCLF TAIFLLMALS NSTFARRSVT VDILICALFG
SLTVISTKAL SGLLVKDVAG AFTHQITYVA LIVLLLTAAA QVHFLNKALN RFHSKIVIPT
QYIYFTISVI FSSSVLFNDL DSFPYPTLLL GLVVSFCGVF FLCRAPESEQ QELERGCVRR
CSIESAQVQV HSRDLSHPAH TTCIKPIRAR SNSSLTKVGI GLSPAQYLLA SHAGYSDEQQ
PLLHEDESRI LSQTYNSTAN HGDQVQDRYD R
//
