ID R9AXM2_WALI9 Unreviewed; 596 AA.
AC R9AXM2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Anoctamin transmembrane domain-containing protein {ECO:0000259|Pfam:PF04547};
GN ORFNames=J056_000183 {ECO:0000313|EMBL:EOR04836.1};
OS Wallemia ichthyophaga (strain EXF-994 / CBS 113033).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Wallemiomycotina;
OC Wallemiomycetes; Wallemiales; Wallemiaceae; Wallemia.
OX NCBI_TaxID=1299270 {ECO:0000313|EMBL:EOR04836.1, ECO:0000313|Proteomes:UP000014064};
RN [1] {ECO:0000313|Proteomes:UP000014064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-994 / CBS 113033 {ECO:0000313|Proteomes:UP000014064};
RX PubMed=24034603; DOI=10.1186/1471-2164-14-617;
RA Zajc J., Liu Y., Dai W., Yang Z., Hu J., Gostincar C., Gunde-Cimerman N.;
RT "Genome and transcriptome sequencing of the halophilic fungus Wallemia
RT ichthyophaga: haloadaptations present and absent.";
RL BMC Genomics 14:617-617(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KE007224; EOR04836.1; -; Genomic_DNA.
DR RefSeq; XP_009265856.1; XM_009267581.1.
DR AlphaFoldDB; R9AXM2; -.
DR GeneID; 20373135; -.
DR KEGG; wic:J056_000183; -.
DR eggNOG; KOG2513; Eukaryota.
DR HOGENOM; CLU_010867_1_0_1; -.
DR OMA; VEEHENQ; -.
DR OrthoDB; 49329at2759; -.
DR Proteomes; UP000014064; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF73; INCREASED SODIUM TOLERANCE PROTEIN 2; 1.
DR Pfam; PF04547; Anoctamin; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..536
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
SQ SEQUENCE 596 AA; 67088 MW; A08354991576D602 CRC64;
MPSLETAKVD LIVVYKLSSS DAHLKALHQL QSSFSWAVRP GSNDDEVLAF LQAKQSTRRS
VDSECNNLYD YFMVHYASPD VKKVVIPHNH DFNKTLISDL TSSYLLSNQQ LTSIKNAFGV
NVGFYFAFLR SYFRSLILPS LIGFFCWFRS SQFSSFYAIF VSLYAVAFVE YWRVAERALS
VQWGSDGSKS IELTRVERER TAWYVRESKL MATLPVLALF AMLLAALLTI IFFIEEFGLQ
FYNGPLKSYI SLILSAVCSG IVPLLITAYQ PVLNKLSRWE NHATHSDTEA SLTIKSFTLN
SLVSFAGLAL TAYVYIPFGK DLVKAASKRF EKFEIFGTNE IVEIDGSRIQ TQLFAQMVTS
QAIGTFQEVG LPYIMSFVRS HISKNTYTPK DAPEERDYLQ AVREEVAKDT YDLFEDYAEM
VTQFGFISLW SVAWPLAPLM GLINNFFEIR GDAFKLIKHY SRCIPRSTDS IGPWLDALSF
LSWLSAMINT SLVILFNTSF KNSGILAAHG GVLVAFVAAL VASHGHFVIK GIFARLFKIA
IWDNSASAAI VRDRALALHS SARCSKSNKD RPLDNDEIKL RQTVNEMNSS ISKKDN
//
