ID   R9H6I6_9SPHI            Unreviewed;       789 AA.
AC   R9H6I6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=ADIARSV_0042 {ECO:0000313|EMBL:EOR96779.1};
OS   Arcticibacter svalbardensis MN12-7.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Arcticibacter.
OX   NCBI_TaxID=1150600 {ECO:0000313|EMBL:EOR96779.1, ECO:0000313|Proteomes:UP000014174};
RN   [1] {ECO:0000313|EMBL:EOR96779.1, ECO:0000313|Proteomes:UP000014174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MN12-7 {ECO:0000313|EMBL:EOR96779.1,
RC   ECO:0000313|Proteomes:UP000014174};
RX   PubMed=23846277;
RA   Shivaji S., Ara S., Prasad S., Manasa B.P., Begum Z., Singh A.,
RA   Kumar Pinnaka A.;
RT   "Draft Genome Sequence of Arcticibacter svalbardensis Strain MN12-7T, a
RT   Member of the Family Sphingobacteriaceae Isolated from an Arctic Soil
RT   Sample.";
RL   Genome Announc. 1:E00484-13(2013).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOR96779.1}.
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DR   EMBL; AQPN01000001; EOR96779.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9H6I6; -.
DR   STRING; 1150600.ADIARSV_0042; -.
DR   PATRIC; fig|1150600.3.peg.41; -.
DR   eggNOG; COG3525; Bacteria.
DR   eggNOG; COG3534; Bacteria.
DR   Proteomes; UP000014174; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 3.90.182.10; Toxin - Anthrax Protective Antigen;domain 1; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   InterPro; IPR037524; PA14/GLEYA.
DR   InterPro; IPR011658; PA14_dom.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF13290; CHB_HEX_C_1; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   Pfam; PF07691; PA14; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SMART; SM00758; PA14; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF56988; Anthrax protective antigen; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   PROSITE; PS51820; PA14; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000313|EMBL:EOR96779.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EOR96779.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014174}.
FT   DOMAIN          649..786
FT                   /note="PA14"
FT                   /evidence="ECO:0000259|PROSITE:PS51820"
FT   ACT_SITE        356
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   789 AA;  88054 MW;  60DAD11C21FCA019 CRC64;
     MKNLNKYRNP VTLDIIQVVS EIKRILIASS IFMVGFAGLA NAQDNNPSLG IIPAPVLLKK
     SIGTFMLSQQ TTLLADSVMN KAVVFFQDYL LNKGMLKIKL KPNSGLIPAN SIVLTSQGAD
     KLPPDGYILL ITPQKITITG RGAGLFYGIQ SLIQLMPGGK AGAASLPCVE IEDYPRFKYR
     GLMLDVCRHF FSVEFVKRYI DLMAAYKVNN FHWHLTDDQG WRIEIKKYPK LTQVSSLRAQ
     TVIGDFHDRT PQQYDNTPYG GFYTQDQIRE VVKYASARYV NIIPEIEMPG HSEAVFAAYP
     ELSCNPSLTT YKVAETWGIF HNIYCPSEQT FDFLQNVLTE VMDLFPGKYI HIGGDEAPKD
     AWKKSEFCQK LIKKLGLKDE EELQSYFIQR IEKFVNSKGR NIIGWDEILE GGLSPNATVM
     SWRGEAGGIA AARQNHHVIM TPGSAGLYID QLQGKQNIEP LNNGGNAPLD KIYRYNPIPA
     ELTSDQQKYI QGVQANLWAE YIATEKKAEY MILPRMLALS EVGWTSLSNK NFADFTNTRL
     PSHLAWLDKN NFNYRVPAAI GSQDTIVFGS QLNVNLTSPV NGAKIYFTID GYPPRETDME
     YTVPMHYNVP AGQYRELKTI VITPSGKRSQ VTHTVMYNQL PFEAINYNGT SKGLKYRLYT
     GGFTSTNQLK DEAVIDSGVS LSFNTSAFKN NMKGFGLLFN GFIHIDADDV YGFSTSSANG
     SVLLIDNQPV VDNDGKHGLF DQGGAVPLKK GYHKITIKYF DATSSGNLKV FISATGKPKS
     EINPAMLFY
//