ID R9IN19_9FIRM Unreviewed; 1792 AA.
AC R9IN19;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=LPXTG-domain-containing protein cell wall anchor domain {ECO:0000313|EMBL:EOS23299.1};
GN ORFNames=C806_02804 {ECO:0000313|EMBL:EOS23299.1};
OS Lachnospiraceae bacterium 3-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397288 {ECO:0000313|EMBL:EOS23299.1, ECO:0000313|Proteomes:UP000014188};
RN [1] {ECO:0000313|EMBL:EOS23299.1, ECO:0000313|Proteomes:UP000014188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-1 {ECO:0000313|EMBL:EOS23299.1,
RC ECO:0000313|Proteomes:UP000014188};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the serine-aspartate repeat-containing protein
CC (SDr) family. {ECO:0000256|ARBA:ARBA00007257}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS23299.1}.
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DR EMBL; ASST01000018; EOS23299.1; -; Genomic_DNA.
DR STRING; 397288.C806_02804; -.
DR PATRIC; fig|397288.3.peg.3064; -.
DR eggNOG; COG4932; Bacteria.
DR HOGENOM; CLU_001476_0_0_9; -.
DR OrthoDB; 9804660at2; -.
DR Proteomes; UP000014188; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 13.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR013552; Thioester_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR PANTHER; PTHR36108:SF13; COLOSSIN-B; 1.
DR PANTHER; PTHR36108; COLOSSIN-B-RELATED; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17802; SpaA; 13.
DR Pfam; PF08341; TED; 1.
DR SUPFAM; SSF49478; Cna protein B-type domain; 3.
DR SUPFAM; SSF117074; Hypothetical protein PA1324; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000014188};
KW Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..1792
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004483736"
FT TRANSMEM 1762..1781
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1752..1792
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
SQ SEQUENCE 1792 AA; 196175 MW; ABC3A46E0E34E545 CRC64;
MKQKMKRFMA GFLALLTVFT TLFGNGMTAF AANSSANIAF WYASTRASGE VSELKAGYDH
GKILYAILDG NAAYCMNFGL AADGGQLMNS YPNSSTSMTA QQEKLLSYCL YFGFNSNSAT
APSNDQCDQF IATQAMVWVI VGNLFGTDGG DSAARKLCDT APNPSSSYAY YTSLKSSISK
SYNATRPSFA SRTQSGAETY ELKWNEGNQR FEKTLTDSNG VLGDFDISLS GYKVEKNGNS
VTISSREVNT AATMATMNST AGEVETTSSC VFWLTEKANY QEFVSERPSA DPIHAYFKVK
TENIGYGEIV KTDESSGVKL KGAVYGIYSD SGCTNKADTM TTDGNGYAKS SALAAGTYYV
KEITAPKGYV LSGKVHTLTV KAGQTTGISA TDKEQLGAIT IYKEGEVLTG WNGSNFTYEK
KKLPGAVFRV TAGADIYRAD GTKVYSNGDV IAENLVAGSD GQVVLTDLHL GTYVVTETKS
IDGYTINTEP HTVKIEYKDQ MAEVQYEATT VLNTRQKAEV SVTKKDSETT NPLDGGQYTL
YAGSDIRNYA GEVIATKGTA LQTVTTGEDG SAAYTVDLPI ANSYYISETQ APYAYYRNSS
DVYSFAFNYL PETTAKAAFT HTFTNDRTTA KIHIYKVDKE TGKAVPQGDA KLEGAVYGLY
ARDDIAHPDG ATGIIFHAGD LVATMTTDAG GNAEVKNLYL GNYYVKEITP SEGYLLDEEE
HDVVCDYEGD LVAEVSRSTT SPEQVIKQPF QLIKVSDNGD DTEAPVLSGA GFTAYLKSSL
SVLEDGSYDF DSAKPVEIGS KGETTLFTDA KGHIVTQPIP YGTYVVVETV TPHNMQPVRP
FEVRIVENHP TEPQVWRVFI DREFTAKLRV IKKDADTKQT VLIPNTEFKI FNLDKNEYVK
MVTTYPSKVT HTSFFTDEDG DLILPDVLKI GNYRIEEVKA PYGYVLNTNY VEVAVDSDTF
YETDPDTYDA IITVEYEDEP VVGELTVEKK GEILDGYKGG LFADSEEKEF VYREGSLAGA
KFEVYAAEDI YTADMQTDGD GNRTRYYRKG ELVGTLTTGE DGKASISGLP LGQYRVVETE
APYGYVLNGE EQLVTFVYVD DKTPVIYENV TFTNDRQKLD MSVIKKDAEE DTPVAGAKFG
LFAAEDIENA NGEVIIEAGT FLETAVSDEN GRIAFKKDYP FAVYEAKELA APKGYVSSEE
VVTFETEYQG QHEAVAEYSS EFLNEPTTFE FTKEDIASGA ELSGAMLTVI DKDGNVVDRW
TSVAGEAHVI KRLTAGETYT LREEFAPYGY LKAEEIQFTV EDTADIQSAV MKDEVPTGAI
IINKDGEFVT DTTLMKGHWY DFIFNYFKDS LAGVEFEVYA AEDIVSPDGL DTIYYEADEL
VATIVTDEKG YAGIDSLPLG KYYLVETKTL EGFVLDDTPI EADLSYIDQE TAVVYAGMNI
SNERQKVQIT VVKKEAGTKE VLEGAVFGLF AKEDIVNKDG KVVVKAGTEI ERGVTGKDGK
LTFVSDLPLG KYYVQELTAP KGYVKSDKVF DVDASYQGDD KEVIEFEAEF ENKPIKVQIS
KTDITGDNEL EGAVLSVIDA DGNLVEKWTS GKEPHMIEKL PAGKYILREE TAPFGYVIAQ
DIEFEVKETD EIQKVAMKDE AAVGKIIISK KSEDGKALAG AKFEIRDTDG KVIETLTTDK
DGHAESSELP IAAFKDGKYE EAVTYTVVEV EAPKGYLLDS TPKEVKFEYK DGKTKVALYT
LEVTNKPTEP KLPQTGDNMN PWVFAGFGLA AVAAGLAALF WKKRKDGDGA EA
//
