ID R9IN41_9FIRM Unreviewed; 2894 AA.
AC R9IN41;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C806_02834 {ECO:0000313|EMBL:EOS23329.1};
OS Lachnospiraceae bacterium 3-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397288 {ECO:0000313|EMBL:EOS23329.1, ECO:0000313|Proteomes:UP000014188};
RN [1] {ECO:0000313|EMBL:EOS23329.1, ECO:0000313|Proteomes:UP000014188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-1 {ECO:0000313|EMBL:EOS23329.1,
RC ECO:0000313|Proteomes:UP000014188};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS23329.1}.
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DR EMBL; ASST01000018; EOS23329.1; -; Genomic_DNA.
DR STRING; 397288.C806_02834; -.
DR PATRIC; fig|397288.3.peg.3092; -.
DR eggNOG; COG0553; Bacteria.
DR eggNOG; COG0827; Bacteria.
DR eggNOG; COG4646; Bacteria.
DR HOGENOM; CLU_000181_0_1_9; -.
DR Proteomes; UP000014188; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000014188}.
FT DOMAIN 2055..2304
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 2445..2642
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 251..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 975..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1051
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1297..1324
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2161..2215
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2805..2860
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 251..295
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..323
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..994
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2894 AA; 329705 MW; 68E74D7BB2E5B675 CRC64;
MSADTKTSKL YDAAIDEVTA SGQAWKSICR LTGQLYRYEF DNILMVYKQR PRATLIADFD
TWKMVGRYVR RGSKGIAIFP SRALKPDMRY VFDISDTGGR ESRLTWELDR NTVKAYAAWL
REKEGAALPG GKESDKSFLK DFTERQIGVI MDSEFGERIT EFVNLAGNKQ ITENGRAQEI
TAVEALKRSV MYAVFTRCGF DLPTEKQDFS FITAFTTEEE VYRLGSLLSD ISCGVLRGIA
KDLKQMEERS IANGRDNNDV SRGNGRDAVP GHHDTGGNGE HDKLREVRSE GDGVPEREPQ
QQIPDAAEIR ETGREDAGSG GRSEPDDGRA GGQLLKEQPA EGPKLDNGDV AATAAGEDAG
RGNRDERSSD EVPLGDSGQQ TEENEQQNIR KAELDREIEQ ELNEINSLGS SETQKGSYEQ
ASFLIAANGD IEVPKEYSYQ KPEQALTVPH EYVKQVLMRG GVFSGSKKRI YAMFQDISDP
GERVKAVRKE YGQGGAGWPL EGDGLHGYDT FHAKGLRFQW REGGTEIEGY MNWKAVEREL
GALIMTGEYY TPPKAFDPDK ISAAVWQEPM DEFFQKSFWS PVPNMLLYEV FTKELPMSDK
AQFIERVLCR NPYAASTENN LENEYGRCNI EQNNEGISIE YFDGEGTKWK TELDWWDCAA
YVESMIADGA YQTHEPYDKI GEIMEEHPAA TWIKILKEDT DRYLSEDAGQ HQQNRLENLH
TILEAKGIRE KIELSWDDAY DEVIASDGEN VWHGRQFYDY LYNEVLASDK IRRDGSIPYN
VQQQFEHDRF SSHNPDKTNF IHRKTFITLE LTADEWEKQE ESLWLEPLKG YFNEEIQYIS
VKTLIYDIFT TNLNMESKAG FLASVYGEQR EGFFMSEYTD NSFGKCKISR DKDGIEISYP
RADGTKGEKR VDYRYCADLI LHMIEENDYL TEGIFERFRE APGAFAAMPW FMEIYHEYKE
RMLQEPDFAA VSIDGQEEER QEGQETEAAA EEIPETRQTA ENGQEEIPGT WQAVENGQEE
IPEAWQTAES GQEETAETQQ EETAEVQPGQ EDIQETAERV EGEVINPDGS VAKPAAGSLF
PEALRQVEEM DGDLRDALET YLTKCSAVVP YQPFLQMVAE SSLPKEDKLN FLNRTINHLE
DKEQTKAYHN NAYGLVEYIQ NRDAFMVDLK SRDGERERFS ATYEQLYSIM EYLIKAQMFT
GEIRMSAYLR DFAKLPYEKM SALEKQFDDK LTSLRNRQRK GNFHFEEAEL PKGGPKTRYQ
WNVEAIRLLK QIEHEDRTAT PEEQKVLARY VGWGGIAQAF DERNNDWQKE YAELKELLST
SEYEDARETV NTAFYTSPVI TQAVYNALDK FGFRKGTILE PALGVGHFFG TLPETMQDSR
LYGVEKDDIS GRIAKLLYPK AQIKVRGFEE TQYPDNFFDV AVGNVPFGDY KLYDAKYAKH
NFRIHDYFFA KALDKVRPGG IVAFITSKGT LDKANPSVRK YLAERAELLG AIRLPNTAFK
DSAGTDVTSD IIFLQKRERK IVTEPDWVHL GRTEDGIAVN SYFAGHPEMM LGTMEYDTRM
FGNGSKYTSC INHDENFDLK SALETAVGQL SGRITDVAEL AAEEENTEDI IEADPDVKNY
TYTFVDGKLY YRENSVMYRK EVSATAEERI KGMDEIRTIT RQLIFIQTEG CSSEELAAQQ
KLLNDRYDAY VKKYGPLTGR GSQQAFRDDA DYPLLCSLEV VDEDGKVEKA DMFYKQTIRA
KNQVERVETA VEALNVSVNE FGTVNIPFML SIYEPDISKE IESLSEGSTL SPDAEAEVKR
SVLLKDLEGL VYLEPTEYNP DNLNTGWKTA DEYLSGNVRD KLRIAEVYRK ENPELFGVNT
EALKNVQPER LDASEIDVRI GTTWIEPQDY EEFIYELLKT PYRARAVRTQ YTNSGIQVKL
NTYNMNWFID GKRHDNHSVA ATETYGTKRI DAYSIFEETL NLRTVTVRDR IDDGGGKYHY
EVNKKETMLA REKQNQMKEA FKSWIFKDQE RRQKYVDYYN ETFNNIRLRE YDGSHLTFPG
MNPEIKLRDH QKNAIARVLL GGNTLLAHCV GAGKTFTMMA ACMEQRRLGL ANKNVIVVPK
SIVGQTAGEF MRLYPSANIL VATERDFEKS RRKQFVSRIA TGDYDCIIMS HSQFEKIPIS
KERKERMLQD QIQEISFAID EIKAEKGEQW TIKQMEAQKK KLDEQLKELT EESRKDDLIT
FEELGIDSVM VDEAHHFKNL SIFSKINNVS GISSTGSKKA MDMYLKCQYL DEINDGRGIV
FATGTPVSNT MCELYVMQLY LQKRTLERMG IYHFDSWAAN FGEVTTALEL TVEGSGFKFK
SRFNKFTNVP ELMTSFREVA DVQTADMLNL PVPALREGKP IIVESEPDWY VKQVMEEFAK
RAERIHGGGV DPKEDNFLKI TGEARLLGTD ARLLELDAPN NPDGKLNKVA ANVAAEYFAG
NRDGKIGCQL IFSDIGTPKT TWTPDWAERI KNGGQFDIYN YLKTELVKQG IPAEEISFIH
DAKTDAQREA LFKDMRSGKK KILIGSTDQC GTGVNVQAHI TAMHHVDCPW KPSCIEQREG
RGVRQGNEND EVAIYRYVTK GTFDAYSWSL VENKQRFISQ VMTSRAVSRT CEDIDEATLS
YAEIKAVATG NPLIKEKMQL ENDVQRLKML KSSYDSQRYS LQDNFMIRYP KLIKAATEKL
ACVREDTKTA EAALIAEPDF AITVDVAGKS TKFTERTDGG TFMLQAVSQC KTGETTHIGS
FKGFELLVEK NFIGVNNMVL RGKTDYKAEL STSPVGNMVK LENLCHGIQV NIPELEKRIE
QYQRDMEQSR QEYEKPFTQE EELNEKVARL NELNVQLDLE NGKTEDVDLC ETQDNARVAE
PGTYHCFPSG KEGR
//
