ID R9IUQ9_9FIRM Unreviewed; 399 AA.
AC R9IUQ9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Tyr recombinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C806_01715 {ECO:0000313|EMBL:EOS25588.1};
OS Lachnospiraceae bacterium 3-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397288 {ECO:0000313|EMBL:EOS25588.1, ECO:0000313|Proteomes:UP000014188};
RN [1] {ECO:0000313|EMBL:EOS25588.1, ECO:0000313|Proteomes:UP000014188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-1 {ECO:0000313|EMBL:EOS25588.1,
RC ECO:0000313|Proteomes:UP000014188};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS25588.1}.
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DR EMBL; ASST01000010; EOS25588.1; -; Genomic_DNA.
DR AlphaFoldDB; R9IUQ9; -.
DR STRING; 397288.C806_01715; -.
DR PATRIC; fig|397288.3.peg.1864; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_027562_17_4_9; -.
DR OrthoDB; 9801717at2; -.
DR Proteomes; UP000014188; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008907; F:integrase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004191; Integrase_Tn916-type_DNA-bd_N.
DR InterPro; IPR025269; SAM-like_dom.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF02920; Integrase_DNA; 1.
DR Pfam; PF13102; Phage_int_SAM_5; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00023195};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000014188};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 86..167
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 190..395
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 399 AA; 45752 MW; 3E4523BB16885091 CRC64;
MGDTTSDKRK DGKKRNLKTG ESMRKDGRYA YKYKGADGKP KFAYSWRLTK TDPLPEGKRD
CKPLREIEKE IQRDLMDGIN HTGAKMTVCE LYAKHTELKS NVRESTKKGR KQLMTILEND
KIGNMQVEKV KPTDAKEFVK RMREQGYAFN TINNYKRFLK AIFYTAIQDD LIRKNPFNFS
TDDVIENDTA EKIVLADTQA DLLLQFLQTD CTYQKHYHAV TVLLNTGLRI SELCGLTVKD
IDFENGYINV DHQLIFDRGN YRTEKPKTDS GIRKIPMTEP VSKALKDEIN NRENVQPVTV
DGYTDFVFLN KKGLPMYGAA YSVDFGNMIK KYNKHHKKKL PKISPHTLRH TFCTNMANKN
MPPKALQYIM GHKDITTTLG YYAHGSAESA KTALKSLTA
//
