ID   R9J819_9FIRM            Unreviewed;      1143 AA.
AC   R9J819;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=BIG2 domain-containing protein {ECO:0000259|SMART:SM00635};
GN   ORFNames=C804_03261 {ECO:0000313|EMBL:EOS30335.1};
OS   Lachnospiraceae bacterium A4.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397291 {ECO:0000313|EMBL:EOS30335.1, ECO:0000313|Proteomes:UP000014118};
RN   [1] {ECO:0000313|EMBL:EOS30335.1, ECO:0000313|Proteomes:UP000014118}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A4 {ECO:0000313|EMBL:EOS30335.1,
RC   ECO:0000313|Proteomes:UP000014118};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A4.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS30335.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ASSR01000064; EOS30335.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9J819; -.
DR   STRING; 397291.C804_03261; -.
DR   eggNOG; COG3209; Bacteria.
DR   HOGENOM; CLU_277398_0_0_9; -.
DR   Proteomes; UP000014118; Unassembled WGS sequence.
DR   Gene3D; 2.60.40.1080; -; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR003343; Big_2.
DR   InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR   InterPro; IPR026906; LRR_5.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45661:SF3; RICH REPEAT DOMAIN PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR45661; SURFACE ANTIGEN; 1.
DR   Pfam; PF02368; Big_2; 1.
DR   Pfam; PF13306; LRR_5; 3.
DR   SMART; SM00635; BID_2; 2.
DR   SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014118}.
FT   DOMAIN          295..369
FT                   /note="BIG2"
FT                   /evidence="ECO:0000259|SMART:SM00635"
FT   DOMAIN          374..449
FT                   /note="BIG2"
FT                   /evidence="ECO:0000259|SMART:SM00635"
SQ   SEQUENCE   1143 AA;  123901 MW;  8065C7EC9A10CA7E CRC64;
     MAGLLEDLSR INVVNIPDTV VRIGSRSIKG ASITELALPE KLTVIEDSAF ENCTKLTSVT
     WHDHTLEKIG NAAFKGCTAV KGLTLAQENV AESSTEAAQI IELPDSVTVI GEEAFSGLKL
     PQKLIWSRCL SDLGANVFSG CTGISVVRFA DSEETMHLLE IPASLEQCGA SPLADANITS
     AVWEEGSDTI LSNIVQGLGI TSVEIPKTVL TIQDNAFKNC TKLVTIDIPK SVTSIGAAAF
     QNCSALEDAI IPKFVRKIGG SENIFDGAVR LTIRGVVGSY INTYADTYAI PFERLISTCT
     LAQDSFDIPK GEAVILSVTD LWSGEEPVFT SDDSTVAVTA ENGIVTGTGV GATTLKVNID
     NSYFATATIQ VCSPMKELAL DFHEMELHIN DTEAVVVSYL PEDTTDQKTA HYSIADTNVA
     SVDDNGNVTA LALGETTLTI TVEATTWTAE TGYGKTEITT NCKIQVIPDD QLKKHQKKRP
     NPISVITNVC PTTGEIDEEL LEGWSFVTSN EQILLENGGV NTFAIEYIEN GYETLTVTAT
     EITDLSFINR IYRIPLAGSK PVIFTTTPVF AGAELPAGLY RIEYTSSDEA VARINAATGE
     ITPQGIGTCS MTAALSILDN RKSVVYDELF TVSVPVTVSA STENTKPRIE GSYILNLVQG
     KTRLDIDAVY GTDIEAVSLT GDDAENFRIS KENGGFYIRP NGTVRKKNYK KLALSVKLNE
     SSEAHEKAIT VKVISEMPKI TIKQNSTINL FDKTSFASFK VSGKYMDIAD ICINSDSADA
     SFFAITYDRE SRTGTIQQTG KLDGLSNLKS LTKAQKTLTL NAVFDEYPDA ANQKITLNVK
     TAYKAPSLSI REGKTRIYSL QSLNTLMTVY DKTTKENLTD YTVNTGTMSG SFTAGYDIET
     GKLLIGMKEG TTPANGNYKM TASALFENDM PSLKKNFTIS VHNKTPQIKL SAKGSIDILN
     PHSAVYYTPK LTNVSGTITG VSLSGSNAEA FRADLLADNR IRLTLAHTQN SNAKITANTK
     YSLQFCFTLD NSLLLMAYPT TVSIKPIQSK AKITASSTKL TMDYFEKELD FLLTQPETAE
     IERVVLADTQ NFNYSYDAKA LTLKDNHNLT AGKTYTLQFN IFCKTEAKTT NPVTVKIKVT
     IPK
//