ID R9JEI5_9FIRM Unreviewed; 563 AA.
AC R9JEI5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=phosphoenolpyruvate carboxykinase (ATP) {ECO:0000256|ARBA:ARBA00012363};
DE EC=4.1.1.49 {ECO:0000256|ARBA:ARBA00012363};
GN ORFNames=C807_00621 {ECO:0000313|EMBL:EOS32391.1};
OS Lachnospiraceae bacterium 28-4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397287 {ECO:0000313|EMBL:EOS32391.1, ECO:0000313|Proteomes:UP000014112};
RN [1] {ECO:0000313|EMBL:EOS32391.1, ECO:0000313|Proteomes:UP000014112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28-4 {ECO:0000313|EMBL:EOS32391.1,
RC ECO:0000313|Proteomes:UP000014112};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 28-4.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate;
CC Xref=Rhea:RHEA:18617, ChEBI:CHEBI:16452, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216;
CC EC=4.1.1.49; Evidence={ECO:0000256|ARBA:ARBA00001389};
CC -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC {ECO:0000256|ARBA:ARBA00004742}.
CC -!- SIMILARITY: Belongs to the phosphoenolpyruvate carboxykinase (ATP)
CC family. {ECO:0000256|ARBA:ARBA00006052}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS32391.1}.
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DR EMBL; ASSU01000009; EOS32391.1; -; Genomic_DNA.
DR AlphaFoldDB; R9JEI5; -.
DR STRING; 397287.C807_00621; -.
DR PATRIC; fig|397287.3.peg.673; -.
DR eggNOG; COG1866; Bacteria.
DR HOGENOM; CLU_037428_0_0_9; -.
DR OrthoDB; 9806325at2; -.
DR UniPathway; UPA00138; -.
DR Proteomes; UP000014112; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004612; F:phosphoenolpyruvate carboxykinase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.228.20; -; 1.
DR Gene3D; 3.40.449.10; Phosphoenolpyruvate Carboxykinase, domain 1; 1.
DR InterPro; IPR001272; PEP_carboxykinase_ATP.
DR InterPro; IPR013035; PEP_carboxykinase_C.
DR InterPro; IPR008210; PEP_carboxykinase_N.
DR Pfam; PF01293; PEPCK_ATP; 1.
DR SUPFAM; SSF68923; PEP carboxykinase N-terminal domain; 1.
DR SUPFAM; SSF53795; PEP carboxykinase-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000313|EMBL:EOS32391.1};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Pyruvate {ECO:0000313|EMBL:EOS32391.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014112};
KW Transferase {ECO:0000313|EMBL:EOS32391.1}.
SQ SEQUENCE 563 AA; 62409 MW; 4BC167B6A4411510 CRC64;
MSTKAYYPIS EIGAGKVGFS KTRSIIEAAF YGNNVVKVNT LKEAYELAKN SPGTVVTDMK
IKDGETFGLE KDSRVLLFND GAVTGRYAAA RRIKGEPGVD EVKLDKVVMD AIYETRWKTM
YHAECFIGLD PEFMAKAHLL IPEGEENILY NWMLNFQYMS DEYVKMYRNS KAIGDGNEPD
IYIFSDPQWV PGNRPDVDYS CLSDPLTLCY FDTNQNCAAI LGMRYFGEHK KGTLTMAWAL
ANRNGYASCH GGQKEYLLPG GKTFVASVYG LSGSGKSTLT HAKHGGKYEI KVLHDDAFII
NTDTCASVAL EPTYFDKTAD YPTGCADNEY LLSAQNCSCT LDNEGKIQLV TEDIRNGNGR
AIKSKLWSPN RVDKIDAPVN AIFWIMKDPT IPPVVKLKGA ALASVMGATL ATKTSTAERV
AAGTDLNALR IVPYANPFRT YPLVNDYEKF KKLVEEKNVD CYIINTGDFM GKKVKPADTL
GILEAIVEER ASFTQWGPFE DIEIMDWEGF APDLNDAEYK EALKNAMQNR VDAVEGFATK
KEGYDKLPDE ALAAVKKLVD ALN
//
