ID   R9JK65_9FIRM            Unreviewed;       230 AA.
AC   R9JK65;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Sensor histidine kinase NatK C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C804_01579 {ECO:0000313|EMBL:EOS34331.1};
OS   Lachnospiraceae bacterium A4.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397291 {ECO:0000313|EMBL:EOS34331.1, ECO:0000313|Proteomes:UP000014118};
RN   [1] {ECO:0000313|EMBL:EOS34331.1, ECO:0000313|Proteomes:UP000014118}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A4 {ECO:0000313|EMBL:EOS34331.1,
RC   ECO:0000313|Proteomes:UP000014118};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A4.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS34331.1}.
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DR   EMBL; ASSR01000030; EOS34331.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9JK65; -.
DR   STRING; 397291.C804_01579; -.
DR   PATRIC; fig|397291.3.peg.1612; -.
DR   eggNOG; COG3290; Bacteria.
DR   HOGENOM; CLU_020211_9_2_9; -.
DR   Proteomes; UP000014118; Unassembled WGS sequence.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR   Gene3D; 1.10.287.130; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR   InterPro; IPR039506; SPOB_a.
DR   PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   Pfam; PF14689; SPOB_a; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014118};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          35..87
FT                   /note="SpoOB alpha-helical"
FT                   /evidence="ECO:0000259|Pfam:PF14689"
FT   DOMAIN          128..229
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   230 AA;  26285 MW;  F4F8BBBEA75A5CB3 CRC64;
     MIFQTKKVKV KGIFIEKLID RRIAAYQSEL LATHYAEVEN MYRKMRGWRH DYRNHIQVLK
     SYADMGALDE LRRYLDELGN DLDTVDLALK TGNKMTDVIL NSKISLAKSK EIAVTVDAHV
     AVALTTAEID LCIIIGNLFD NAIEANMALP KEERMIRVYM DMKNTQLYMS FTNRTAAKKQ
     HKVNGRFLTS KGTGHGYGLV RIDTIVERYQ GYISRNSEDG AFTTEILLPQ
//