ID R9JKQ5_9FIRM Unreviewed; 456 AA.
AC R9JKQ5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=AI-2E family transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=C807_01037 {ECO:0000313|EMBL:EOS31727.1};
OS Lachnospiraceae bacterium 28-4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397287 {ECO:0000313|EMBL:EOS31727.1, ECO:0000313|Proteomes:UP000014112};
RN [1] {ECO:0000313|EMBL:EOS31727.1, ECO:0000313|Proteomes:UP000014112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28-4 {ECO:0000313|EMBL:EOS31727.1,
RC ECO:0000313|Proteomes:UP000014112};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 28-4.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS31727.1}.
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DR EMBL; ASSU01000012; EOS31727.1; -; Genomic_DNA.
DR AlphaFoldDB; R9JKQ5; -.
DR STRING; 397287.C807_01037; -.
DR PATRIC; fig|397287.3.peg.1112; -.
DR eggNOG; COG0628; Bacteria.
DR HOGENOM; CLU_031275_2_0_9; -.
DR OrthoDB; 9793390at2; -.
DR Proteomes; UP000014112; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR21716:SF75; TRANSPORT PROTEIN SLL0063-RELATED; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014112};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 412..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 456 AA; 51031 MW; CD744104F22A8468 CRC64;
MKFRIDKKYI HWGMTAFSVI AASIFFYYLL FHRESISSGF HTFVSVTMPI LDGLLLSYLL
TPILNGVEKR CLIPLCIRYH IDVNERGRKK IRIISIILTV IIVGFVVYSF FAMIIPQLVN
SIQSIVLQFP IYVNNLTIWV KKLLADNPDI EAAVIEVMDN YSIELNNFLN LSLLPKMNEL
IKDISLSFLT FLKGLWNLIL GFIISIYILG SKELFAGQAK KIVYALFETN SANAIISDVR
FTHRTFSGFM VGKVIDSIII GIICFFGTSL MGTPYAILIS VIVGITNIIP FFGPYLGAIP
SALLILMVDP LQCLYFIIFI LVLQQFDGNV IGPKILGNST GLSGFWVIFS ITLFGGIFGI
LGMIAGVPIF AVIYAGIRAI VNQLLLKKEL PTDTKDYLNV GTIEEGEFIP YKAEGRSKSS
SDDSSGDGKT RPKSIIHHFF RNNNTDHTLP EEEEDK
//
