ID   R9JND1_9FIRM            Unreviewed;       559 AA.
AC   R9JND1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=C808_04684 {ECO:0000313|EMBL:EOS35481.1};
OS   Lachnospiraceae bacterium M18-1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235792 {ECO:0000313|EMBL:EOS35481.1, ECO:0000313|Proteomes:UP000014090};
RN   [1] {ECO:0000313|EMBL:EOS35481.1, ECO:0000313|Proteomes:UP000014090}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M18-1 {ECO:0000313|EMBL:EOS35481.1,
RC   ECO:0000313|Proteomes:UP000014090};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium M18-1.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS35481.1}.
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DR   EMBL; ASSV01000041; EOS35481.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9JND1; -.
DR   STRING; 1235792.C808_04684; -.
DR   ESTHER; 9firm-r9jnd1; Carb_B_Bacteria.
DR   PATRIC; fig|1235792.3.peg.5081; -.
DR   eggNOG; COG2272; Bacteria.
DR   HOGENOM; CLU_006586_16_4_9; -.
DR   Proteomes; UP000014090; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014090}.
FT   DOMAIN          45..543
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   559 AA;  63088 MW;  37D370974C8CDE55 CRC64;
     MTLSAAFRND TDSIADRFSC GQRCCKQWVT VRSMIQGRRK MDGYIAETKN GKIRGYEREG
     RIEYLGIPFA KPPVGELRFK RAVPMDAWEG ILEAREYGPE SVQLDEGELK GSEDSLTLNI
     QRPLEGGNLP VFVWIHGGGY NTGAASVPLY NGKAFVRDGL IFVSFQYRMN VLGFYDFTTY
     PGCGDFDSNC GISDQIMALT WIHENIAAFG GDPDQVTIAG ESAGGASVVN MLAIPAVKGM
     FRQAVIQSAL PNCVCTHQTA RENIDLFLEG MGWTEDDLPK LRTEDPYEFQ KGNTYVAEKH
     QYKNPGMFLP GPVIDDLLPV RPIDAIRGGS AAGVKIIIGT NQDEGTMFVH PEKTGFPNSW
     AMVAEMFEKN GNASALPDII NYYHPSARDR FQEFRAQGEF TQNAVPDVQS HFRTEGGDPF
     IEFATDYAFQ MPALKVAEAQ RKYNDVWMYR FEFVSINGEK TGWKASHAFD IPCVFANKDF
     KFSRFLFEGE TEETKNALIE AMHTPWVRFA KTGEPDPENW PKYDGYNSEI RIFDRKTTTK
     LVRRKELMDV WGELRFYED
//