ID R9JS60_9FIRM Unreviewed; 440 AA.
AC R9JS60;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Type 3 secretion system ATPase {ECO:0000256|ARBA:ARBA00024442};
DE EC=7.4.2.8 {ECO:0000256|ARBA:ARBA00024382};
GN ORFNames=C804_00444 {ECO:0000313|EMBL:EOS36968.1};
OS Lachnospiraceae bacterium A4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397291 {ECO:0000313|EMBL:EOS36968.1, ECO:0000313|Proteomes:UP000014118};
RN [1] {ECO:0000313|EMBL:EOS36968.1, ECO:0000313|Proteomes:UP000014118}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A4 {ECO:0000313|EMBL:EOS36968.1,
RC ECO:0000313|Proteomes:UP000014118};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium A4.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O + cellular proteinSide 1 = ADP + phosphate +
CC cellular proteinSide 2.; EC=7.4.2.8;
CC Evidence={ECO:0000256|ARBA:ARBA00034006};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family. T3SS ATPase
CC subfamily. {ECO:0000256|ARBA:ARBA00024342}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS36968.1}.
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DR EMBL; ASSR01000007; EOS36968.1; -; Genomic_DNA.
DR AlphaFoldDB; R9JS60; -.
DR STRING; 397291.C804_00444; -.
DR PATRIC; fig|397291.3.peg.455; -.
DR eggNOG; COG1157; Bacteria.
DR HOGENOM; CLU_022398_5_1_9; -.
DR OrthoDB; 9802718at2; -.
DR Proteomes; UP000014118; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0030257; C:type III protein secretion system complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-EC.
DR GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:UniProtKB-EC.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR CDD; cd18114; ATP-synt_flagellum-secretory_path_III_C; 1.
DR CDD; cd18117; ATP-synt_flagellum-secretory_path_III_N; 1.
DR CDD; cd01136; ATPase_flagellum-secretory_path_III; 1.
DR Gene3D; 3.40.50.12240; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR020003; ATPase_a/bsu_AS.
DR InterPro; IPR004100; ATPase_F1/V1/A1_a/bsu_N.
DR InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR InterPro; IPR005714; ATPase_T3SS_FliI/YscN.
DR InterPro; IPR013380; ATPase_T3SS_SctN.
DR InterPro; IPR022425; FliI_clade2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR040627; T3SS_ATPase_C.
DR NCBIfam; TIGR03497; FliI_clade2; 1.
DR NCBIfam; TIGR01026; fliI_yscN; 1.
DR NCBIfam; TIGR02546; III_secr_ATP; 1.
DR PANTHER; PTHR15184; ATP SYNTHASE; 1.
DR PANTHER; PTHR15184:SF9; SPI-1 TYPE 3 SECRETION SYSTEM ATPASE; 1.
DR Pfam; PF00006; ATP-synt_ab; 1.
DR Pfam; PF02874; ATP-synt_ab_N; 1.
DR Pfam; PF18269; T3SS_ATPase_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000313|EMBL:EOS36968.1};
KW Cilium {ECO:0000313|EMBL:EOS36968.1};
KW Flagellum {ECO:0000313|EMBL:EOS36968.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000014118};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 161..342
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 440 AA; 48277 MW; 0EA20EE54B4D8234 CRC64;
MESCISFDKY KTVLNKSFFK KLGKVENVVG LTIESSGPDA KLGDMCKIYT DAEKQHGILA
EVVGFKDKKT LLMPYEDTEG IGLGCIVENM NYPLSVSVGD SLLGKTLDGL GRCIDGFVPE
PTTVKRYPLE AMPPDPMSRT IISEVLPLGV KAVDGLITVG KGQRIGIFAG SGVGKSTLMG
MFARNTKADI NVIALIGERG REVREFIERD LGEEGMRRSI VVVATSDRPA LERNKAAKTA
TAIAEYFRDQ GKDVLLMMDS LTRFSMAQRE IGLATGEPPV TRGYPPSVYS EMPKLLERAG
CSESGSITGL YTVLVEGEDF NEPITDTARS ILDGHIMLTR KLANRNHYPA VDVLQSISRC
MSMIASREHK AAAGKLKNIM ATYNEAEDLI NIGAYKRGSN PNIDRAINKI DEVNQYLLQD
TDAKFTFEES VEQLEAMFQE
//
