ID R9JVT4_9FIRM Unreviewed; 443 AA.
AC R9JVT4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Sensor histidine kinase NatK C-terminal domain-containing protein {ECO:0000259|Pfam:PF14501};
GN ORFNames=C808_02505 {ECO:0000313|EMBL:EOS38304.1};
OS Lachnospiraceae bacterium M18-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235792 {ECO:0000313|EMBL:EOS38304.1, ECO:0000313|Proteomes:UP000014090};
RN [1] {ECO:0000313|EMBL:EOS38304.1, ECO:0000313|Proteomes:UP000014090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M18-1 {ECO:0000313|EMBL:EOS38304.1,
RC ECO:0000313|Proteomes:UP000014090};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium M18-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS38304.1}.
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DR EMBL; ASSV01000016; EOS38304.1; -; Genomic_DNA.
DR AlphaFoldDB; R9JVT4; -.
DR STRING; 1235792.C808_02505; -.
DR PATRIC; fig|1235792.3.peg.2687; -.
DR eggNOG; COG3290; Bacteria.
DR HOGENOM; CLU_020211_14_0_9; -.
DR OrthoDB; 9156435at2; -.
DR Proteomes; UP000014090; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014090};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 337..439
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 443 AA; 50405 MW; 70F5BF5C168B179E CRC64;
MTLAYIINDL LFVVPCILLL LLVFWDQLKT PTIFWIFTGG SLFLAVSLWG TYIYFLFDTP
VYHLLIAVFS MFFGVLIFSS ACRYNFWQGL FIIAVVKSYS ENVRFLSYDF YFLLKGTLPR
QPILQIALIT TLLTVLTFPA IWLLYKKLMR PALDYTVSLA VWKWVWLIPV SGNAVYTVTV
APECSSYSLR PENGFFLIPP LWAFLTFSTY AVLLKMMIDV NKNAVLRENL HLSETQIAAQ
QKQMELLQSN IRKTSRIRHD IRHHFLAMEG LLKDNDIEGL KAYIHQSIAL FPVQSAKVFC
DSPAVNSLLC YYMEQAEKEQ ADISANVSLQ DVIPIPDAEL CIIIGNLLEN AVEACQRMKS
QERFLDVKLS MPSSSILMVQ VCNSYEGTVQ QMADGSFLSS KRKAQKGIGL SSVLSITEKY
NGIARIEHQK QLFQVSVIIS QNP
//
