ID   R9JZY8_9FIRM            Unreviewed;       345 AA.
AC   R9JZY8;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Peptidase M15B domain-containing protein {ECO:0000259|Pfam:PF02557};
GN   ORFNames=C809_04582 {ECO:0000313|EMBL:EOS39663.1};
OS   Lachnospiraceae bacterium MD335.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235793 {ECO:0000313|EMBL:EOS39663.1, ECO:0000313|Proteomes:UP000014081};
RN   [1] {ECO:0000313|EMBL:EOS39663.1, ECO:0000313|Proteomes:UP000014081}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COE1 {ECO:0000313|EMBL:EOS39663.1,
RC   ECO:0000313|Proteomes:UP000014081};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium COE1.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS39663.1}.
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DR   EMBL; ASSW01000084; EOS39663.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9JZY8; -.
DR   STRING; 1235793.C809_04582; -.
DR   PATRIC; fig|1235793.3.peg.4787; -.
DR   eggNOG; COG1876; Bacteria.
DR   HOGENOM; CLU_054193_0_0_9; -.
DR   OrthoDB; 9792074at2; -.
DR   Proteomes; UP000014081; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd14852; LD-carboxypeptidase; 1.
DR   Gene3D; 3.30.1380.10; -; 1.
DR   InterPro; IPR009045; Hedgehog_sig/DD-Pept_Zn-bd_sf.
DR   InterPro; IPR003709; Pept_M15B.
DR   PANTHER; PTHR34385; D-ALANYL-D-ALANINE CARBOXYPEPTIDASE; 1.
DR   PANTHER; PTHR34385:SF1; PEPTIDOGLYCAN L-ALANYL-D-GLUTAMATE ENDOPEPTIDASE CWLK; 1.
DR   Pfam; PF02557; VanY; 1.
DR   SUPFAM; SSF55166; Hedgehog/DD-peptidase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014081};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        51..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          188..323
FT                   /note="Peptidase M15B"
FT                   /evidence="ECO:0000259|Pfam:PF02557"
SQ   SEQUENCE   345 AA;  39901 MW;  760D1F1D0B598347 CRC64;
     MKRTWKDNIT AIIKQKIKQN RRLKLPMTVC IIVITIFYNT CYHFAHNTRR FASVLAVIVF
     FVASSSFSFL SEEERMGIMP ESQEWAQIQE NYEYVPTTFH IPAADMIDDN DVLEGYDNKE
     LEVEVSKIDQ YSLDDFLEAE AAGEAQQVKS PSLAKLSKDD WQLVLVNKQH PVPDDYTFTL
     GTIKGKMKCD ARIIDDLTEM MKAAKADGIN LMVCSPYRDY NRQTVLFNRK IDYYMEKGYS
     YLEAYKISSM TVTVPGASEH QIGLALDIIS STYYALDEGF GETKAGIWLR EHCDEYGFIL
     RYPLGKEYIT GIQYEPWHFR YVGREAAHNI MERGITLEEF LEDLD
//