ID R9K379_9FIRM Unreviewed; 478 AA.
AC R9K379;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Sensor histidine kinase NatK C-terminal domain-containing protein {ECO:0000259|Pfam:PF14501};
GN ORFNames=C809_04446 {ECO:0000313|EMBL:EOS40874.1};
OS Lachnospiraceae bacterium MD335.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235793 {ECO:0000313|EMBL:EOS40874.1, ECO:0000313|Proteomes:UP000014081};
RN [1] {ECO:0000313|EMBL:EOS40874.1, ECO:0000313|Proteomes:UP000014081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COE1 {ECO:0000313|EMBL:EOS40874.1,
RC ECO:0000313|Proteomes:UP000014081};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium COE1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS40874.1}.
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DR EMBL; ASSW01000078; EOS40874.1; -; Genomic_DNA.
DR AlphaFoldDB; R9K379; -.
DR STRING; 1235793.C809_04446; -.
DR PATRIC; fig|1235793.3.peg.4655; -.
DR eggNOG; COG3290; Bacteria.
DR HOGENOM; CLU_020211_2_1_9; -.
DR Proteomes; UP000014081; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014081};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 368..476
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 478 AA; 53543 MW; E2A2F654E669934C CRC64;
MAEWVMGLIS VLLCLFEGYC IQSFFGGFAV PKLCRIRNAG WAAGIAWIVI RAFSQGLFSD
MDSVSLIIEL LFTFCTLFVF CVCWYRGNVL LKIFLAVQFI SLRELSFWTG YSLLYIGNEM
IEVLVHKAGT SAAEYLPVAA GILSCFGAVL VVATKCALLF VSTRKIAGSY CNKERGRMGK
EVLFYLLPSV AGTLVSVLVR LLLITVTDGA PVLLYEKYPV LYLIIPMIAL VLLGAIVFSF
RIYQNMAALQ EERAEKIILE NQITQMQGSM VEMEHLYDGV RSVKHDMKNH MAVLQNLIQK
KYSGEDEEIR QYFEGMYQSV EQLDSRVHTG NAVSDAVVGS KFRYAAKKVK GIKLDARGFM
LSDAVTIKAY DMGIILNNGL DNAIEACMKM REKQPYAEAY ITIRSFRAKN MYFIEIENSF
DGMALFDKES GLPISTKEDK EVHGIGLKNI RKCAVKYGGD MDCIVKGNRF TLSVMVKS
//
