ID R9KCI5_9FIRM Unreviewed; 543 AA.
AC R9KCI5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Leucine-rich repeat domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C810_03312 {ECO:0000313|EMBL:EOS44154.1};
OS Lachnospiraceae bacterium A2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397290 {ECO:0000313|EMBL:EOS44154.1, ECO:0000313|Proteomes:UP000014150};
RN [1] {ECO:0000313|EMBL:EOS44154.1, ECO:0000313|Proteomes:UP000014150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A2 {ECO:0000313|EMBL:EOS44154.1,
RC ECO:0000313|Proteomes:UP000014150};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium A2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS44154.1}.
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DR EMBL; ASSX01000019; EOS44154.1; -; Genomic_DNA.
DR AlphaFoldDB; R9KCI5; -.
DR STRING; 397290.C810_03312; -.
DR PATRIC; fig|397290.3.peg.3669; -.
DR eggNOG; COG5492; Bacteria.
DR HOGENOM; CLU_501338_0_0_9; -.
DR OrthoDB; 2068400at2; -.
DR Proteomes; UP000014150; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45661:SF3; RICH REPEAT DOMAIN PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR45661; SURFACE ANTIGEN; 1.
DR Pfam; PF13306; LRR_5; 2.
DR SUPFAM; SSF52058; L domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014150};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..543
FT /note="Leucine-rich repeat domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004475707"
FT TRANSMEM 516..533
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 402..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 543 AA; 53295 MW; 71006AE25EE53AFB CRC64;
MKKLFGRCFN VILILALTFA LGPALPAMAE EDVSAFIMEG GTITGYTGPG GDVVLPASAT
AVADYAFAGN AAISSVTIPA NVTSVGSYAF SGCTGLTNAV FGGPVSLGGG AFYGCSALGY
VDLPAGLSAI GAETFDGCSS LGSVNIPEGV TSIGAQAFNG CGSLGSINIP GSVSEIGSSA
FNNCVGLGSI TIPDSVSSMG SGVLAGCSGL SSVTLSSGMS SIPELTLYGC SSLGSVSIPG
SVGSIGSQAF GNCSGLGSIS IPASVSSIDF SAFDGCSNLA EVNVEGGNGS YASSDGAVYD
AGMSQLLYCP VGKSQLTLPD SMTSIASAAF SNSPYVYGLD IPSSVTTIEV DAFTGSGIKA
VTIPPTTTSI GSQSGWTPDV IRGYTGSQAE KFADENGYIF ESIGNLGEDT PTPTPTPDPT
DKPTKTPKPN DPTEDPTETP EPGDPTNTPG PNGGGTTGNG TTGGTTGGTT GGTSGGRTQT
GSGGGTSAGS RTSVSRNMGT AQVGSGTPKT GVAFDAKYVL CLGVFFAGGY LVINKKKKGA
NAE
//
