ID   R9KD18_9FIRM            Unreviewed;       462 AA.
AC   R9KD18;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=BIG2 domain-containing protein {ECO:0000259|SMART:SM00635};
GN   ORFNames=C810_03519 {ECO:0000313|EMBL:EOS44360.1};
OS   Lachnospiraceae bacterium A2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397290 {ECO:0000313|EMBL:EOS44360.1, ECO:0000313|Proteomes:UP000014150};
RN   [1] {ECO:0000313|EMBL:EOS44360.1, ECO:0000313|Proteomes:UP000014150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A2 {ECO:0000313|EMBL:EOS44360.1,
RC   ECO:0000313|Proteomes:UP000014150};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS44360.1}.
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DR   EMBL; ASSX01000019; EOS44360.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9KD18; -.
DR   STRING; 397290.C810_03519; -.
DR   eggNOG; COG5492; Bacteria.
DR   HOGENOM; CLU_591592_0_0_9; -.
DR   Proteomes; UP000014150; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.380; -; 2.
DR   Gene3D; 2.60.40.1080; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR003343; Big_2.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR   Pfam; PF02368; Big_2; 1.
DR   SMART; SM00635; BID_2; 1.
DR   SUPFAM; SSF89260; Collagen-binding domain; 1.
DR   SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014150};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        23..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          271..348
FT                   /note="BIG2"
FT                   /evidence="ECO:0000259|SMART:SM00635"
SQ   SEQUENCE   462 AA;  51131 MW;  8A7EBFB67EF8A9D2 CRC64;
     MLFAGLGAAN ENERKGKNMK QKLLKWATAL TSCIVLLLFC GIHVQAAEYS IGTNDSWAEG
     STEKEGIDYR TFTLPAAGRV TVTYQSYMSN GRCNLYDKDL VTNYKYVRTS GSTTAPATEQ
     FSMDLEAGAY SLKLSGGYWN AGDDPSSYRV KVSFVPAHNN EKEPNDAFES AMPLANGTLI
     KGFLSEDDSI DFYRFSIGES ANVRTTVSRD TIGSYKFSIW NSDLIEVASY TTSEQTKVWE
     EYLAPGTYYI KINKDWDATG TYILKWEGFT YVKVIQLKKS ALTLEKGKSY SLLQSITPAS
     ANNKNIKWTS DNTSVAKVDS HGKVTAKGVG AANIKAAAMD GSQVEATCQV VVKPAKTQIT
     ACKKTRDRNV YVKVKAQKNV SGIQFQLSRD KKFKGRKSSY YAGATETKAT TAALKKSKTY
     YFRARMYIDY GGKRYYGAWS QVKKVKTGKK SRLSGSSSWK AV
//