ID   R9KRG1_9FIRM            Unreviewed;       937 AA.
AC   R9KRG1;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Fibronectin type-III domain-containing protein {ECO:0000259|PROSITE:PS50853};
GN   ORFNames=C810_00175 {ECO:0000313|EMBL:EOS49074.1};
OS   Lachnospiraceae bacterium A2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397290 {ECO:0000313|EMBL:EOS49074.1, ECO:0000313|Proteomes:UP000014150};
RN   [1] {ECO:0000313|EMBL:EOS49074.1, ECO:0000313|Proteomes:UP000014150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A2 {ECO:0000313|EMBL:EOS49074.1,
RC   ECO:0000313|Proteomes:UP000014150};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS49074.1}.
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DR   EMBL; ASSX01000001; EOS49074.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9KRG1; -.
DR   STRING; 397290.C810_00175; -.
DR   PATRIC; fig|397290.3.peg.197; -.
DR   eggNOG; COG2340; Bacteria.
DR   eggNOG; COG3209; Bacteria.
DR   HOGENOM; CLU_322829_0_0_9; -.
DR   OrthoDB; 1908369at2; -.
DR   Proteomes; UP000014150; Unassembled WGS sequence.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.1080; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR   InterPro; IPR026906; LRR_5.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45661:SF3; RICH REPEAT DOMAIN PROTEIN, PUTATIVE-RELATED; 1.
DR   PANTHER; PTHR45661; SURFACE ANTIGEN; 1.
DR   Pfam; PF00041; fn3; 1.
DR   Pfam; PF13306; LRR_5; 3.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014150};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           34..937
FT                   /note="Fibronectin type-III domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004484994"
FT   DOMAIN          842..937
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          639..671
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          744..769
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   937 AA;  99815 MW;  F18B6CCC84F2D0DC CRC64;
     MKKTKRAKRM LAGLLALLLA VTGVPLSGME VRAADEVLTD GNFYYMVNKD GKSVMITHYN
     SGETTETSVT IPSEIDGKSV TAIGNEAFYQ NTSLTSLTIS GNVSYIGNSA FEGCTKLANL
     SLPDSITTVD FCAFKGCTNL ADFTIPEGIT SIGDSAFKDC TSLTSLTIPD SATSISSDTF
     SGCSNLETIK VKEGNTVYDS RNNCNAIIQT GNNTLISGCK NSHIPEGITS IAPYAFQECN
     GLEALTIPDS VTSIGECAFY GCSSLTALAI PNNVTSIGYS AFKGCSGLKS VNIPNNLSTI
     EHTTFKDCSS LESLTIPSSV DTIWNHAFEN CSNLANLNLL PGCCSYAIHS EAFLGCTSLT
     SLTIPNIGPI NSYAFGYKRN DFNKDLKEKI SGFTIYGKKG SEAETYATEN GFSFITSAMI
     SDASITLEGE DDGYVWDGTP KTPAITVKLD GKTLTEGIDY TVFYNNNTEI GRAEVIVTGM
     GSYHGSTAVN FSISETGWEG DFKYKVNEDG NSVTILKYDG ANNDAKIPET IAGKTVTVIG
     EEAFSLWSSW FSSDSPASLT IPASVTSIGS YAFYHWRNLK SITIPSTVTS IGYHAFGFCE
     YEVDPDDGGD ISDKKVADFT IYGESGSAAE AYATKNGFPF NQPATGGDSG TTPGTGPSQN
     GGSQGTPSQA DLSKATVTLE KDAYPYDGKA KTPAVTVTLN GKTLSPSTDY TVSYTDNVNV
     GTAKATVTGK GNYKGSVTKT FTITKANNPA GNNGTSDGNG SAGTSNSKQP ITCKKRAYTV
     AYGTKPFRLK VTSNGSLTYK SSNRKIAAVG KTNGKVTIKN TGIAYITAKT KTDSVKITIK
     VRPAKPKVKS LPTGKNRKLT VKWAKDKRAT GYQVQISTSK NFKKNVKKQN TAKTAYTFKK
     LKAGSKYYVR LRSFKKSGKN TLYSAWSSPK QSGKIKR
//