ID   R9KX30_9ACTN            Unreviewed;       437 AA.
AC   R9KX30;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Galactokinase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C811_01182 {ECO:0000313|EMBL:EOS50766.1};
OS   Adlercreutzia caecimuris B7.
OC   Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC   Adlercreutzia.
OX   NCBI_TaxID=1235794 {ECO:0000313|EMBL:EOS50766.1, ECO:0000313|Proteomes:UP000014204};
RN   [1] {ECO:0000313|EMBL:EOS50766.1, ECO:0000313|Proteomes:UP000014204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|EMBL:EOS50766.1,
RC   ECO:0000313|Proteomes:UP000014204};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Enterorhabdus caecimuris B7.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS50766.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ASSY01000008; EOS50766.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9KX30; -.
DR   STRING; 1235794.C811_01182; -.
DR   PATRIC; fig|1235794.3.peg.1159; -.
DR   eggNOG; COG0153; Bacteria.
DR   HOGENOM; CLU_017814_8_0_11; -.
DR   OrthoDB; 250531at2; -.
DR   Proteomes; UP000014204; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR   InterPro; IPR000705; Galactokinase.
DR   InterPro; IPR019539; GalKase_N.
DR   InterPro; IPR036554; GHMP_kinase_C_sf.
DR   InterPro; IPR006204; GHMP_kinase_N_dom.
DR   InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR   InterPro; IPR006206; Mevalonate/galactokinase.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   PANTHER; PTHR10457:SF35; GALACTOKINASE; 1.
DR   PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR   Pfam; PF10509; GalKase_gal_bdg; 1.
DR   Pfam; PF00288; GHMP_kinases_N; 1.
DR   PIRSF; PIRSF000530; Galactokinase; 1.
DR   PRINTS; PR00473; GALCTOKINASE.
DR   PRINTS; PR00959; MEVGALKINASE.
DR   SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014204};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          22..72
FT                   /note="Galactokinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10509"
FT   DOMAIN          133..223
FT                   /note="GHMP kinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00288"
SQ   SEQUENCE   437 AA;  45341 MW;  E82543028E31F464 CRC64;
     MEVVRAIADE ADAGRWAHLR GLFEEIFGAP REGASFVEAS APGRVEVAGN HVDHQGGRVI
     SAAIGERTWG LAAENGLGRI RAVMEGFGTD EVDLSDPSWA APHPVEALSS AAMVRGMAAL
     FEARGGAVRG FDIVTCSDVP PGCGLSSSAA FEVMLGAALE GLFGPGPFAV SAVDAGAPAG
     DSAASGDVAL DAAAVALAAV ECEQRYFGKP CGAQDQLACA CGGVVTIDFA PKVPVVEPMT
     LDAAAEGYRI VLIDSRQDHS LHQDEFAAIP ADMRMVANLL GVPRLGDAPV DTLLAQLQRV
     RTELGDRRAM RALHYYDEVA RVNAQRAALA AGDFGLFLRE VRLSGASSAQ FLQNVSLREP
     GSEARQPAMV IQSLAAHLLG ERGAWRIHGG GFGGSVLAFV PCAEADGFMG AMDGLLGYAA
     CREVTLGAPG VRAERLP
//