ID R9KZE2_9FIRM Unreviewed; 656 AA.
AC R9KZE2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Methyl-accepting chemotaxis protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C809_01043 {ECO:0000313|EMBL:EOS51586.1};
OS Lachnospiraceae bacterium MD335.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235793 {ECO:0000313|EMBL:EOS51586.1, ECO:0000313|Proteomes:UP000014081};
RN [1] {ECO:0000313|EMBL:EOS51586.1, ECO:0000313|Proteomes:UP000014081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COE1 {ECO:0000313|EMBL:EOS51586.1,
RC ECO:0000313|Proteomes:UP000014081};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium COE1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS51586.1}.
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DR EMBL; ASSW01000016; EOS51586.1; -; Genomic_DNA.
DR AlphaFoldDB; R9KZE2; -.
DR STRING; 1235793.C809_01043; -.
DR PATRIC; fig|1235793.3.peg.1077; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_12_9; -.
DR OrthoDB; 9762005at2; -.
DR Proteomes; UP000014081; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014081};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 305..358
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 410..639
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 656 AA; 70081 MW; D0F214CDDF325F99 CRC64;
MKSIRTKITL CLILTVLVGL IASGVSSIIP NYNSTMTTVE YMMSETAVLA AGRVEQELMA
YKNVVTDTGC VPQLSDPNVS LDEKKKIIDE RCAMHNFQRG NIIGLDGISI FDEKDYSDRE
YVQQAMQGNV YVSEPLISKI TGELSIMVAA PLYEDGTYGA SIAGVVYFVP HETFLNDIVS
AIQIGENSRA YMINKSGDTI ADITLDTITV QNIETQAQSD PSLSELAAIH ANMREGKNGF
GEYESDGHKM FAAYAPVADT DGWSIAVTAP QLNYLASTRD AMVINIAVII IAILVSSVIA
LVLANSISKP MKACAKRMKL LVEGDLDTPM PKITSKDETG MLANSTASLV EGLSTVINDI
AYLLNELANK NLNVHTQHED VYVGSFHSIL LSMRNMKIAL SDALRQVNYS AEQVSAASNQ
LSASAQTLSQ GTTEQASAVE ELAAQVGEIS EQAKHTASGA LDVRKQTHDA GEEVALCNQK
MQTLMGAMDE IQTRSDEIEK ILKTIDDIAF QTNILALNAA VEAARAGEAG KGFAVVAEEV
RNLAAKSAQA AQNTSQLIEH STAAVHTGTG IAKDTADILL NVVNSIQSVV NSIDKIATVS
NEQSDAVWQI SEGINQVSTV VQSNSATAQE GAAASEQLSA EAAVLKQLVN QFTLSS
//
