ID   R9MHA4_9FIRM            Unreviewed;       679 AA.
AC   R9MHA4;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   RecName: Full=Glycosyl hydrolase family 13 catalytic domain-containing protein {ECO:0000259|SMART:SM00642};
GN   ORFNames=C818_02063 {ECO:0000313|EMBL:EOS70091.1};
OS   Lachnospiraceae bacterium MD308.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235799 {ECO:0000313|EMBL:EOS70091.1, ECO:0000313|Proteomes:UP000014117};
RN   [1] {ECO:0000313|EMBL:EOS70091.1, ECO:0000313|Proteomes:UP000014117}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3-2 {ECO:0000313|EMBL:EOS70091.1,
RC   ECO:0000313|Proteomes:UP000014117};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 3-2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS70091.1}.
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DR   EMBL; ASTE01000021; EOS70091.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9MHA4; -.
DR   STRING; 1235799.C818_02063; -.
DR   PATRIC; fig|1235799.3.peg.2176; -.
DR   eggNOG; COG0366; Bacteria.
DR   HOGENOM; CLU_006462_6_4_9; -.
DR   OrthoDB; 9805159at2; -.
DR   Proteomes; UP000014117; Unassembled WGS sequence.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd11338; AmyAc_CMD; 1.
DR   CDD; cd02857; E_set_CDase_PDE_N; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR006048; A-amylase/branching_C.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR004185; Glyco_hydro_13_lg-like_dom.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10357:SF210; MALTODEXTRIN GLUCOSIDASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 2.
DR   Pfam; PF02806; Alpha-amylase_C; 1.
DR   Pfam; PF02903; Alpha-amylase_N; 1.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014117}.
FT   DOMAIN          123..578
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   679 AA;  78816 MW;  ECFD98743DDE89A5 CRC64;
     MNKQALFCDG SRWYVSPQEP DCNQIVTLRF RTAKEDAVRV CLVVGEDRYN ISKESVEGEF
     DYYSIDWKLG EEPFSYCFEI SDKEQVCYFN RCGVAEVRSG LYDFRIVPGF STPEWAKGAV
     MYQIYTDRFY NGDPSNDVET NEYFYIGDYS RKVTDWNKYP DTMGVREFYG GDLQGVMDKL
     DYLQELGVEV LYFNPLFVSP SNHKYDIQDY DYIDPHFGVI VDDGGEVLAD GDRDNVNATK
     YQKRVASLKN LEASNELFVK LVEELHRRGM KIILDGVFNH CGSFNKWMDR ERIYENQEEY
     APGAYISAES PYRSYFEFRD NADGRWPYNG TYDGWWSHDT LPKLNYEGSE ELEEYILKVG
     KKWVSPPYNV DGWRLDVAAD LGHSSEYNHE FWKKFRKVVK EANPNALILA EHYGDPSSWL
     QGDEWDSVMN YDAFMEPLTW FLTGMEKHSD EKNEDLLGNA EYFKSSMNHY MSRMLTPSLE
     VAMNELSNHD HSRFLTRTNH VVGRVAEKGP EAAEEYVNLA VMREAVVMQM TWIGAPTIYY
     GDEAGVCGFT DPDNRRTYPW GNENQELIDF HRDMIRIHKN SQALRNGSIQ LLCEENNILA
     YGRFTEDEQI VVIINNHSDF AEVTVPVWRI GVPMRGKMQR LMYSYVKGYT VSRDEYLVRS
     GEMVVNMGAQ SALVVENIS
//