ID R9MHM0_9FIRM Unreviewed; 441 AA.
AC R9MHM0;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Sensor histidine kinase NatK C-terminal domain-containing protein {ECO:0000259|Pfam:PF14501};
GN ORFNames=C818_01546 {ECO:0000313|EMBL:EOS70520.1};
OS Lachnospiraceae bacterium MD308.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235799 {ECO:0000313|EMBL:EOS70520.1, ECO:0000313|Proteomes:UP000014117};
RN [1] {ECO:0000313|EMBL:EOS70520.1, ECO:0000313|Proteomes:UP000014117}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-2 {ECO:0000313|EMBL:EOS70520.1,
RC ECO:0000313|Proteomes:UP000014117};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS70520.1}.
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DR EMBL; ASTE01000014; EOS70520.1; -; Genomic_DNA.
DR AlphaFoldDB; R9MHM0; -.
DR STRING; 1235799.C818_01546; -.
DR eggNOG; COG3290; Bacteria.
DR HOGENOM; CLU_020211_14_0_9; -.
DR OrthoDB; 3173688at2; -.
DR Proteomes; UP000014117; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 337..440
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 441 AA; 51235 MW; D547234DECB7CB1D CRC64;
MERLIATAMY ARSTFIIIPL AFFCFIPVWQ DAKSSPARLA AKVAAAFALM ETVMFLIYFL
FSSVIANIAS AVLCIVIFFY LYQKEIALKR SHLWFIFMTA CMIGGFTYLF YHLVNIFFHP
AATVDDPAFT DTFFLQLAFE SLLILILALP TRRYLGWLVH HFHEEKVWRV IWLIPASFLA
FSYIFIPYDN SVMFVGRFLE VYIISIFIFF ILILLIYGLF YKIAHSITEN QKMTLKTANL
EIQAQQYHRL QSYMQETSRL RHDFRHQLTV LADMLKTRRY DELEHYLTQS IGSFTDMPLK
YCSSSAVNAI LNHYVSLCRE FGIETRLNIR LKDDFSIEDM DFCVLLGNLL ENAMDACKTL
PEEMREITLK IGQTSEHVIA LYISNPYEEP VSIKAGIFLS TKHEGESQGL KSVRLIVEKY
NGFLDISHEN KLFEVKCLLN I
//
