ID R9N0S8_9FIRM Unreviewed; 272 AA.
AC R9N0S8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=HTH merR-type domain-containing protein {ECO:0000259|PROSITE:PS50937};
GN ORFNames=C817_04102 {ECO:0000313|EMBL:EOS76653.1};
OS Dorea sp. 5-2.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS76653.1, ECO:0000313|Proteomes:UP000014211};
RN [1] {ECO:0000313|EMBL:EOS76653.1, ECO:0000313|Proteomes:UP000014211}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=5-2 {ECO:0000313|EMBL:EOS76653.1,
RC ECO:0000313|Proteomes:UP000014211};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Dorea bacterium 5-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS76653.1}.
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DR EMBL; ASTD01000079; EOS76653.1; -; Genomic_DNA.
DR RefSeq; WP_016220762.1; NZ_KE159718.1.
DR AlphaFoldDB; R9N0S8; -.
DR STRING; 1235798.C817_04102; -.
DR PATRIC; fig|1235798.3.peg.4330; -.
DR eggNOG; COG0789; Bacteria.
DR eggNOG; COG4978; Bacteria.
DR HOGENOM; CLU_065103_2_2_9; -.
DR OrthoDB; 9773308at2; -.
DR Proteomes; UP000014211; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01107; HTH_BmrR; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.20.80.10; Regulatory factor, effector binding domain; 1.
DR InterPro; IPR010499; AraC_E-bd.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR029442; GyrI-like.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR011256; Reg_factor_effector_dom_sf.
DR PANTHER; PTHR30204:SF96; MERR FAMILY REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF06445; GyrI-like; 1.
DR Pfam; PF13411; MerR_1; 1.
DR SMART; SM00871; AraC_E_bind; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF55136; Probable bacterial effector-binding domain; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000014211}.
FT DOMAIN 1..71
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT COILED 72..106
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 272 AA; 31354 MW; 75894331AF74D162 CRC64;
MLRIGDFSKL SRVSIRMLRH YDEIGILHPE SVDDFTGYRY YSESQLPLVG RIQALKSLGF
GLSVIKEILV KYEDVREMER FLLVKRKELE EEALETRQKL MLLDSTLKWM RKDGSLMDYN
VTLKTVPERY VASVRQVIPA YDQEGLLWEI MCRELAGQNV QQATPCYGMA IFHDEGHREH
DPDVEIQNTV VGTYQDTEHV KFKTVPPIQV ASATYKGSYD QISRVNKAVA DWVVANGYDF
DGKSFCIYHV SPSQTDNPEE LVTEVCFPVK KK
//
