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Database: UniProt
Entry: R9N4A8_9FIRM
LinkDB: R9N4A8_9FIRM
Original site: R9N4A8_9FIRM 
ID   R9N4A8_9FIRM            Unreviewed;       157 AA.
AC   R9N4A8;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Sigma-70 family RNA polymerase sigma factor {ECO:0000313|EMBL:EOS78159.1};
GN   ORFNames=C819_00281 {ECO:0000313|EMBL:EOS78159.1};
OS   Lachnospiraceae bacterium 10-1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235800 {ECO:0000313|EMBL:EOS78159.1, ECO:0000313|Proteomes:UP000014134};
RN   [1] {ECO:0000313|EMBL:EOS78159.1, ECO:0000313|Proteomes:UP000014134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10-1 {ECO:0000313|EMBL:EOS78159.1,
RC   ECO:0000313|Proteomes:UP000014134};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 10-01.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS78159.1}.
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DR   EMBL; ASTF01000002; EOS78159.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9N4A8; -.
DR   STRING; 1235800.C819_00281; -.
DR   PATRIC; fig|1235800.3.peg.292; -.
DR   eggNOG; COG1595; Bacteria.
DR   HOGENOM; CLU_047691_3_4_9; -.
DR   Proteomes; UP000014134; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF51; ECF RNA POLYMERASE SIGMA-E FACTOR; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014134}.
FT   DOMAIN          9..74
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          100..150
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
SQ   SEQUENCE   157 AA;  18699 MW;  14F864EAF67A411A CRC64;
     MLMSETIDVE EEYDKIYRYC FYKLRSREKA EDITQETFLR FFASDSYYNR GQRLRYLYTI
     ARNLCVDEWR AHQKELLMAE PEQVKAAEGA EEKMILAVSV KLALEKLDEE EREIILLRYV
     NEISIGTISG IYHLSRFAVY RKLKKAVKHL EILLGKE
//
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