ID   R9N9H2_9FIRM            Unreviewed;       791 AA.
AC   R9N9H2;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Virulence-associated protein E-like domain-containing protein {ECO:0000259|Pfam:PF05272};
GN   ORFNames=C817_04116 {ECO:0000313|EMBL:EOS76667.1};
OS   Dorea sp. 5-2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS76667.1, ECO:0000313|Proteomes:UP000014211};
RN   [1] {ECO:0000313|EMBL:EOS76667.1, ECO:0000313|Proteomes:UP000014211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-2 {ECO:0000313|EMBL:EOS76667.1,
RC   ECO:0000313|Proteomes:UP000014211};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Dorea bacterium 5-2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS76667.1}.
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DR   EMBL; ASTD01000079; EOS76667.1; -; Genomic_DNA.
DR   RefSeq; WP_016220776.1; NZ_KE159718.1.
DR   AlphaFoldDB; R9N9H2; -.
DR   STRING; 1235798.C817_04116; -.
DR   PATRIC; fig|1235798.3.peg.4344; -.
DR   eggNOG; COG5545; Bacteria.
DR   HOGENOM; CLU_018385_1_0_9; -.
DR   OrthoDB; 9763644at2; -.
DR   Proteomes; UP000014211; Unassembled WGS sequence.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR007936; VapE-like_dom.
DR   PANTHER; PTHR34985; SLR0554 PROTEIN; 1.
DR   PANTHER; PTHR34985:SF1; SLR0554 PROTEIN; 1.
DR   Pfam; PF05272; VapE-like_dom; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014211}.
FT   DOMAIN          456..675
FT                   /note="Virulence-associated protein E-like"
FT                   /evidence="ECO:0000259|Pfam:PF05272"
SQ   SEQUENCE   791 AA;  89564 MW;  6C618935F98F5FFA CRC64;
     MKVFVSTGNS RMEKRWNGGE MELEDFVRRI SRTVRTAETV EQYRKLSKAR QDSIKDVGGF
     VMGKLKGGRR KKDCVVFRSA LTLDMDHAVG DVPEQMELFF DFRCLIYSTH KHTPEAPRFR
     LVIPLSRNVS PDEYAAVARK VAEDIGMELF DDTTYEPSRL MYWPSTSADG EFVFRDVAGE
     ILDPDVVLAR YRDWRDSSEW PVSGRQQAVV LREMKKQADP LGKEGVVGAF CRTYSIEEAV
     EVFLADVYRP SVMQGRYDYV PADSQAGVVV YEGRFAYSHH ATDPACGKLM NAFDMVRIHR
     FGELDVRASE DTEACKLPSF RAMSEFAVSD ERVKLTLAEE RAESAKREFS GEDDWRKGLE
     LDRQGKVKDT LDNLVLAIRH DDGLQSIAFN LHRDGIDAGE GLPWKQIKPG WNDSDFASLK
     VYLNKGYGVY APTKTKDALL AVASERAYHP VKEYLDALPE WDGVKRVDTL LTDYLGAEDS
     AYTRAVIRKT LAAAVARIYQ PGTKFDSVLI LNGPQGIGKS TMFARLAGAW FSDSLTLTDM
     RDKSGPEKLQ GYWILELGEL AGMKKTDVET VKSFLSRVDD KYRASYGLNV ESHPRQCVIV
     GSTNTESGFL RDITGNRRFW PVRVNGESVK KPWQISGEDV LQVWAEAKAV YEGGERLYLE
     GEVAAMAVSQ QAEAMETDDR EGLVRTYLDT LLPENWDSMS LYDRRNFLNG SEFGEERQTG
     TVRRMMVCNM EIWCECFGRE SSALKKIDSY EISGIMRKIE GWGKYAETKN GMSGFPIYGK
     QRAYVRERDG K
//