ID   R9NB44_9FIRM            Unreviewed;       278 AA.
AC   R9NB44;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=SrtB family sortase {ECO:0000313|EMBL:EOS80539.1};
GN   ORFNames=C817_01595 {ECO:0000313|EMBL:EOS80539.1};
OS   Dorea sp. 5-2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS80539.1, ECO:0000313|Proteomes:UP000014211};
RN   [1] {ECO:0000313|EMBL:EOS80539.1, ECO:0000313|Proteomes:UP000014211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-2 {ECO:0000313|EMBL:EOS80539.1,
RC   ECO:0000313|Proteomes:UP000014211};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Dorea bacterium 5-2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS80539.1}.
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DR   EMBL; ASTD01000030; EOS80539.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9NB44; -.
DR   STRING; 1235798.C817_01595; -.
DR   PATRIC; fig|1235798.3.peg.1703; -.
DR   eggNOG; COG4509; Bacteria.
DR   HOGENOM; CLU_034078_0_0_9; -.
DR   Proteomes; UP000014211; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd05826; Sortase_B; 1.
DR   Gene3D; 2.40.260.10; Sortase; 1.
DR   InterPro; IPR005754; Sortase.
DR   InterPro; IPR023365; Sortase_dom-sf.
DR   InterPro; IPR009835; SrtB.
DR   NCBIfam; TIGR03064; sortase_srtB; 1.
DR   Pfam; PF04203; Sortase; 1.
DR   SUPFAM; SSF63817; Sortase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014211};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   ACT_SITE        165
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT   ACT_SITE        261
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ   SEQUENCE   278 AA;  31877 MW;  2629B5F64A58B4D6 CRC64;
     MSHEEFEDEY ERKELGKSKK RTPKRIKLAI VIALAVVITA GIGAGIYVRS NQKAKAATEQ
     AKKADPEKTA KRYEDLKVEV TIDADDPLYR QIDFEAAKAM NPDVYAWIWI PGTNIDYPIL
     QSGTEDDAYY LNHTIERLEG LPGSIYTEKY NRTDFSDQVT VVYGHNMKDG SMFADLHKYE
     DKQFFESNPY VYIYLPGGQT WKYRIFAAVT FDDRYILGNY SFSLIEDFQS YLDELRGSIN
     GNVDMNIEVT QDTGILTLST CIGDSPNQRW LVNATWEE
//