ID   R9NCX7_9FIRM            Unreviewed;       344 AA.
AC   R9NCX7;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=HTH lacI-type domain-containing protein {ECO:0000259|PROSITE:PS50932};
GN   ORFNames=C817_01403 {ECO:0000313|EMBL:EOS80796.1};
OS   Dorea sp. 5-2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Dorea.
OX   NCBI_TaxID=1235798 {ECO:0000313|EMBL:EOS80796.1, ECO:0000313|Proteomes:UP000014211};
RN   [1] {ECO:0000313|EMBL:EOS80796.1, ECO:0000313|Proteomes:UP000014211}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5-2 {ECO:0000313|EMBL:EOS80796.1,
RC   ECO:0000313|Proteomes:UP000014211};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Dorea bacterium 5-2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS80796.1}.
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DR   EMBL; ASTD01000025; EOS80796.1; -; Genomic_DNA.
DR   RefSeq; WP_016218152.1; NZ_KE159737.1.
DR   AlphaFoldDB; R9NCX7; -.
DR   STRING; 1235798.C817_01403; -.
DR   PATRIC; fig|1235798.3.peg.1505; -.
DR   eggNOG; COG1879; Bacteria.
DR   HOGENOM; CLU_037628_0_1_9; -.
DR   OrthoDB; 569491at2; -.
DR   Proteomes; UP000014211; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   CDD; cd06307; PBP1_sugar_binding; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   InterPro; IPR025997; SBP_2_dom.
DR   PANTHER; PTHR30036:SF7; ABC TRANSPORTER PERIPLASMIC-BINDING PROTEIN YPHF; 1.
DR   PANTHER; PTHR30036; D-XYLOSE-BINDING PERIPLASMIC PROTEIN; 1.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13407; Peripla_BP_4; 1.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014211}.
FT   DOMAIN          3..57
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50932"
SQ   SEQUENCE   344 AA;  38458 MW;  2D90A1A6C3FC0CE6 CRC64;
     MAVTLQQIAE VAGVSRGTVD RALNNRGRIN AEVADKIRRI ADEMGYQPNR AGRALAMAKR
     SITIGVLIQA ADTPFMEKVI EGAEDAKAEV ERLGAEVIIR RMEEFDAPKA VEAMHELRKA
     GCNGIALVPV DDERLKETVN ESVDDNIPVI TFNSDIEESK RLCFVGQDTW QSGRVAAGLM
     ADILPADGKV LVISGYPTSY GHKNRTNGFL KEFAALREDI RVLDVQYDFD DDQMAEMITK
     GMLKEYEDLT GIYLAASGVE GVCRALEELG MEDKVKVISN DLTARNMKYL EEGKIRFLIG
     QDGYRQGYEP VMLLFEKLFD GKEPEKEFAY TEIVIKTRYN IERV
//