ID   R9NE32_9FIRM            Unreviewed;       512 AA.
AC   R9NE32;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=HD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=C819_00369 {ECO:0000313|EMBL:EOS78247.1};
OS   Lachnospiraceae bacterium 10-1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235800 {ECO:0000313|EMBL:EOS78247.1, ECO:0000313|Proteomes:UP000014134};
RN   [1] {ECO:0000313|EMBL:EOS78247.1, ECO:0000313|Proteomes:UP000014134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10-1 {ECO:0000313|EMBL:EOS78247.1,
RC   ECO:0000313|Proteomes:UP000014134};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 10-01.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS78247.1}.
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DR   EMBL; ASTF01000002; EOS78247.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9NE32; -.
DR   STRING; 1235800.C819_00369; -.
DR   PATRIC; fig|1235800.3.peg.384; -.
DR   eggNOG; COG0248; Bacteria.
DR   HOGENOM; CLU_025908_4_1_9; -.
DR   OrthoDB; 9814545at2; -.
DR   Proteomes; UP000014134; Unassembled WGS sequence.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR048950; Ppx_GppA_C.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   Pfam; PF21447; Ppx-GppA_III; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014134}.
FT   DOMAIN          29..306
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
FT   DOMAIN          325..472
FT                   /note="Ppx/GppA phosphatase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21447"
SQ   SEQUENCE   512 AA;  58602 MW;  9F6A89298AEE6116 CRC64;
     MAVKTFAAID VGSYELAMKI FEVSKAKGMR EIDHIRYSID MGSETYSEGK LSSERVDELC
     RILREFSDIM RAYQVSDYKA YGTSAIRETK NKVILLDQVE QRTGIHIDIL SNSEQRFLDY
     KSIALKGEGF QKIIESGTAI LDIGGGSIQI SLFDNDALVS TQNMRLGVLR LQEHLHHLDA
     STRQYDTLIK EMVESQLSVY KKLYLKDRQI KNIIVVDDYI SELVMRKGKG SGGGIADRKT
     LEYYTEACRT KNLSELSRLL NMPEEKISLL YISMVLLHCI MKNVEAERIW APGVTLCDGI
     AYEYAEKNKI ITLPHDFEKD IIACAQSISK RYQGSKKRSE TLEQIALAIF DGMKKIHGLS
     KRERLLLQIA TILHDCGKYI SMVNLGECSY SIIMATEIIG LSHLEREIVA NVVKYNHLEF
     DYETDEYKNQ MVDKAFYLKI AKLIAILKLA NGLDRSHKQK FKNIKISLKE EELIIMADTA
     EDITLEKGLF DERAVFFEEV YKIRPVIRKK RS
//